Highly repetitive fraction of the human genome

Question 1

What type of sequences make up the highly repetitive fraction?

Answer 1

Satellites

Question 2

Are the satellite regions on acrocentric chromosomes part of the highly repetitive fraction?

Answer 2

Nope

Question 3

How can satellite sequences be separated from the rest of the genome?

Answer 3

Density. They have different densities than most human DNA due to sequence content

Question 4

What are repetitive satellite sequences?

Answer 4

Short repeating sequences in long tandem arrays

Question 5

Where are the repetitive satellite sequences found?

Answer 5

Near centromeres and p arms of acrocentric chromosomes, sometimes in secondary constrictions

Question 6

What are minisatellites?

Answer 6

Repetitive sequences with a repeating unit of 10-30 bp

Question 7

Where are minisatellites found?

Answer 7

Subtelomeric regions

Question 8

Why are minisatellites useful?

Answer 8

Some of them vary widely between individuals in number of alleles, making them useful for DNA fingerprinting

Question 9

What are microsatellites?

Answer 9

Repetitive sequences with a repeating unit of 2-5 bp

Question 10

Where are microsatellites found?

Answer 10

Dispersed throughout the genome

Question 11

Why are microsatellites useful?

Answer 11

Good markers for genetic maps