UE & LE Compression Neuropathy (Lecture + Lab) Flashcards
Pathologic changes that occur with neuropathy
Microvascular compression —> ischemia
Thickened epineurium
Myelin thinning distortion
Microtubule closure
Axonal degeneration
Etiologies of nerve entrapment
Increased muscle mass by repetitive activity
Space occupying lesions (cysts or tumors)
Inflammation of surrounding tissues (leads to venous congestion in epineurial and perineurial vascular plexuses —> endoneurial edema -> nerve anoxia)
Posttraumatic conditions — hematoma, fracture, or compression
Systemic causes — pregnancy, hypothyroid, diabetes
3 categories of nerve injury
Neuropraxia (1st degree)
Axonotmesis (2nd degree)
Neurotmesis (3rd, 4th, or 5th degree)
Category of nerve injury involving focal damage of myelin fibers around axon while connective tissue sheath remains intact; limited course (days to weeks); least severe
Neuropraxia
Category of nerve injury in which there is some disruption to the axon itself but myelin sheath remains intact; regeneration is possible, but prolonged (months) without a full recovery
Axonotmesis
Describe 3rd degree neurotmesis and possibility of recovery
Disruption of axon and endoneurium
Recovery through axonal regeneration cannot occur as intraneural fibrosis occurs
Describe 4th degree neurotmesis and possibility of recovery
Disruption of axon, endoneurium, and perineurium (nerve fasciculi); large areas of intraneural scarring at injury site —> precluded axon from advancing distal to level of injury
No improvement in function — surgery is used to restore normal continuity
Describe 5th degree neurotmesis and possibility of recovery
Disruption of axon, endoneurium, perineurium, and epineurium; substantial perineural hemorrhage and scarring occur
Surgery is required to restore neural continuity
Conservative treatment options for compression neuropathy
Activity modifications, use of antiinflammatories, splinting, and/or injections
PT, OMM, pain management
Conservative tx should be pursued for 3-6 months (except with cubital tunnel syndrome — fix right away even in mild cases to avoid nerve damage)
Surgical release is considered when non-operative management fails
Motor, sensation, and reflex associated with C5 nerve root
Motor — deltoid, biceps
Sensation - lateral arm
Reflex - biceps
Motor, sensation, and reflex associated with C6 nerve root
Wrist extension, elbow flexion
Sensation - radial forearm, thumb, index finger
Reflex - brachioradialis
Motor, sensation, and reflex associated with C7 nerve root
Wrist flexion, elbow extension, finger extension
Sensation to middle finger
Triceps reflex
Motor and sensation associated with C8 nerve root
Motor - finger flexion
Sensation ulnar forearm, small finger
Motor and sensation associated with T1 nerve root
Motor - finger abduction
Sensation - medial arm
Possible sites of radial nerve entrapment
High on the humerus
Radial tunnel
At the wrist
Motor and sensory functions of radial n
Motor to triceps brachii, anconeus, wrist extensors
Sensation to majority of dorsum of hand (via posterior interosseous)
Symptoms and treatment of radial nerve compression high on the humerus d/t fracture or compression at spiral groove
Wrist drop, weakness of elbow flexion, possible tricep involvement, +/- tricep reflex diminished, pain/numbness
Tx: function returns in 4-5 mos
What causes supinator syndrome, which involves pain and tenderness 5cm distail to lateral epicondyle as well as wrist drop or pain with resisted supination?
Compression of posterior interosseous branch of radial nerve as it passes under the supinator m. at the arcade of frohse (purely motor branch)
4 possible sites of median nerve entrapment
Ligament of struthers
Pronator syndrome — between superficial and deep heads of pronator teres m.
Anterior interosseous syndrome — just distal to pronator teres, innervates flexors
Carpal tunnel syndrome — flexor tendons under flexor retinaculum
What compression neuropathy?:
Repetitive pronating motions like pianists, fiddlers, baseball players, dentists, weight trainers; c/o achy pain in mid/proximal forearm, aggravated by repeated lifting - may have sensory abnormality in radial 3.5 digits and dx based on pain with resisted forearm pronation
Pronator syndrome
T/F: anterior interosseous syndrome has no sensory symptoms
True
Etiologies of anterior interosseous syndrome
Trauma
Cast pressure
Bulky tendinous origin of ulnar head of pronator teres
Soft tissue masses
Fibrous bands
Tx for anterior interossous syndrome
General tx, and elbow can be splinted in 90 degrees of flexion for up to 12 wks
Pt unable to hold “Ok” sign
Anterior interosseous syndrome
[due to weak flexion ability of index finger’s DIP and thumb’s IP]