TZDs Flashcards
1
Q
TZDs mechanism of action?
A
Increase insulin sensitivity
2
Q
Name the TZDs
A
Rosiglitazone,
Pioglitazone
3
Q
Rosiglitazone AKA
A
Avandia
Black box 2’ cardiac event
4
Q
Avandia AKA
A
Rosigliazone
Black box 2’ cardiac events
5
Q
Pioglitazone AKA
A
Actos
6
Q
Actos
A
Pioglitazone
7
Q
TZDs impact on AIC
A
1-1.5%
8
Q
TZDs - How long to take effect?
A
About 3 weeks,
With full effect taking 8 to 12 weeks to see
9
Q
Contraindications for TZDs
A
Liver fx: if 2 1/2 x normal, watch close, If 3x normal, stop drug Black box for stage 3&4 heart disease Causes wt gain and edema Associated with bladder cancer, Higher in cost
