Dyslipidemia Flashcards
First goal to treat dyslipidemia is:
Get LDL < 100
Statins will decrease LDL how much?
18-55%
Each doubling of dose (up to80 mg/day) will lead to another 7% decrease
Fluvastatin is more/less potent than Simvastatin?
Less
What does fish oil impact?
triglycerides
Which drug(s) should be used first to lower LDL?
Niacin (less than 1g) or ezetimibe
Second goal to treat dyslipidemia?
Raise HDL
HDL is increased with what?
Niacin or fibrates,
Lifestyle modification
Third goal for dyslipidemia?
Decrease triglycerides
What helps to decrease triglycerides?
Glycemic control,
Fibrates, niacin and omega 3s (fish oil)
What amount of weight loss impacts cholesterol?
Sustained weight loss of at least 10%
Which class of drugs are category X and should NOT be used in pregnancy?
Statins