Biguanides Flashcards

1
Q

Biguanides mechanism is action?

A

Increase insulin sensitivity,

Decrease hepatic glucose production

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2
Q

Name the biguanides

A

Metformin

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3
Q

Metformin AKA

A

Glucophage (XR)

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4
Q

Glucophage AKA

A

Metformin

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5
Q

Metformin’s impact on AIC?

A

1-2%

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6
Q

Contraindications for Metformin

A

Severe CHF,
Renal impairment with SCr> 1.4 female or > 1.5 male,
Liver disease, ETOH abuse,
? >80 years old
May reduce B12 (1000 micrograms may do it, to treat)

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