Typical Antipsychotic Meds Flashcards
Which class of medications has the greatest incidence of EPS and NMS
First generation Antipsychotics
Mechanism of action of Typical Antipsychotics
D2 receptor inhibitor (block the dopamine receptor) and also block histamine-1, alpha-1, muscarinic-1 receptors
Haloperidol
Haldol
Fluphenazine
Prolixin
Chlorpromazine
Thorazine
Thioridazine
Mellaril
Which first generation antipsychotic is no longer used because it causes severe cardiac arrhythmias that can lead to death?
Mellaril
Blocking the histamine-1 receptors results in what?
Weight gain; sedation
Blocking the alpha-1 receptor results in what?
Orthostasis; hypotension; priapism (sexual dysfunction)
Trifluoperazine
Stelezine
Perphenazine
Trilafon
Loxapine
Adasuve
Pimozide
Orap
Thiothixene
Narvane