Typical Antipsychotic Meds Flashcards

1
Q

Which class of medications has the greatest incidence of EPS and NMS

A

First generation Antipsychotics

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2
Q

Mechanism of action of Typical Antipsychotics

A

D2 receptor inhibitor (block the dopamine receptor) and also block histamine-1, alpha-1, muscarinic-1 receptors

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3
Q

Haloperidol

A

Haldol

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4
Q

Fluphenazine

A

Prolixin

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5
Q

Chlorpromazine

A

Thorazine

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6
Q

Thioridazine

A

Mellaril

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7
Q

Which first generation antipsychotic is no longer used because it causes severe cardiac arrhythmias that can lead to death?

A

Mellaril

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8
Q

Blocking the histamine-1 receptors results in what?

A

Weight gain; sedation

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9
Q

Blocking the alpha-1 receptor results in what?

A

Orthostasis; hypotension; priapism (sexual dysfunction)

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10
Q

Trifluoperazine

A

Stelezine

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11
Q

Perphenazine

A

Trilafon

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12
Q

Loxapine

A

Adasuve

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13
Q

Pimozide

A

Orap

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14
Q

Thiothixene

A

Narvane

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