Mood Stabilizers/Anti-epileptics Flashcards
Valproic Acid
Depakote
Phenytoin
Dilantin
P450 inducer
Dilantin
Carbamazepine
Tegretol
Lamotrigine
Lamictal
Gold standard for tx of Bipolar Disorder
Lithium
Mood stabilizers that can cause Steven Johnson’s Syndrome
Lamictal, Tegretol, and Oxycarbazine
What mood stabilizer causes Ebstein Anomally?
Lithium
What mood stabilizer cause Fetal Hydantoin Syndrome?
Dilantin
Cautions are agranulocytosis, SIADH, and Potent P450 inducer
Carbamazepine
Cautions/ADRs are thrombocytopenia, LFT elevation, Neural tube defects and Pancreatitis
Valproic Acid
Cautions/ADRs are nephrogenic DI, Hyper/Hypo thyroidism, CKD & Ebstein Anomally
Lithium
Modulation of Phosphonositol pathway
Lithium
Increases Na channel inactivation and increases GABA concentration
Valproic Acid
Glutamate inhibition
Lamictal