Types of DNA damage Flashcards

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1
Q

what are common types of errors?

A

spontaneous mutations called depurination and deamination

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2
Q

what is depurination?

A

loss of A or G

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3
Q

what is Deamination?

A

Change of C to U

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4
Q

What are induced types of DNA damage?

A

Radiation and chemicals

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5
Q

what does radiation do?

A

produces thymine dimers, sunlight can cause this

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6
Q

what do chemical errors do?

A

intercalate (insert) into DNA strands

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7
Q

how many proteins are devoted to DNA repair?

A

50

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8
Q

what are the basic steps for repair?

A
  1. endonuclease excises damaged DNA
  2. DNA polymerase fills in the gap
  3. Nick sealed by DNA ligase
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