Types of Cell-cell signaling

Question 1

Endocrine signaling

Answer 1

• Long-range signaling, passes through the circulation

Question 2

Paracrine signaling

Answer 2

• Short-range cell-cell communication via secreted signal molecules that act on neighboring cells
• generally, include growth factors and most (but not nearly all) signal molecules involved in cancer.

Question 3

Autocrine signaling

Answer 3

• Signal acts on the same cell that released the signal

Question 4

Intracrine signaling

Answer 4

• Ligand-receptor interaction occurs entirely within a cell; the signal is never secreted from the cell.

Question 5

Juxtacrine signaling

Answer 5

Signaling by direct contact