Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

HYPERSENSITIVITY BOOK > Type IV Hypersensitivity > Flashcards

Type IV Hypersensitivity Flashcards

1
Q

What type of hypersensitivity reaction is characterized by sensitized T cells, rather than antibodies, being responsible for the symptoms that develop?

A) Type I hypersensitivity
B) Type II hypersensitivity
C) Type III hypersensitivity
D) Type IV hypersensitivity

A

D) Type IV hypersensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Which of the following best describes the time frame of a Type IV hypersensitivity reaction?

A) Immediate reaction within seconds to minutes after contact with the antigen.
B) Reaction occurring within 12-24 hours after contact with the antigen.
C) Delayed reaction - 48-72 hours reaction after contact with the antigen.
D) Reaction that occurs a week or more after contact with the antigen.

A

C) Delayed reaction - 48-72 hours reaction after contact with the antigen.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which subset of T helper (Th) cells is primarily responsible for releasing cytokines in Type IV hypersensitivity reactions?

A) Th0 cells
B) Th2 cells
C) Th1 cells
D) Th17 cells

A

C) Th1 cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Type IV hypersensitivity reactions are characterized by which of the following?

A) Activation of B cells and antibody production.
B) Formation of immune complexes that deposit in tissues.
C) Release of cytotoxic chemicals by eosinophils.
D) Release of cytokines that induce inflammation and tissue damage.

A

D) Release of cytokines that induce inflammation and tissue damage.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which of the following is a characteristic feature of Type IV hypersensitivity?

A) Tuberculosis
B) Robert Koch 1890 - Mycobacterium Tuberculosis
C) L-3 and GM-CSF induce hematopoiesis; monocyte chemotactic protein (MCP-1/CCL2)
D) Contact dermatitis

A

D) Contact dermatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which condition is commonly associated with Type IV hypersensitivity?

A) Granulomas
B) Delayed hypersensitivity - Mycobacterium tuberculosis, Mycobacterium leprae, Pneumocystis carinii, Leishmania species, and herpes simplex virus
C) Robert Koch 1890 - Mycobacterium Tuberculosis
D) L-3 and GM-CSF induce hematopoiesis; monocyte chemotactic protein (MCP-1/CCL2)

A

A) Granulomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which pathogen is known to trigger Type IV hypersensitivity reactions?

A) Robert Koch 1890 - Mycobacterium Tuberculosis
B) L-3 and GM-CSF induce hematopoiesis; monocyte chemotactic protein (MCP-1/CCL2)
C) Tuberculosis
D) Granulomas

A

A) Robert Koch 1890 - Mycobacterium Tuberculosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the role of L-3 and GM-CSF in Type IV hypersensitivity?

A) Granulomas
B) Tuberculosis
C) L-3 and GM-CSF induce hematopoiesis; monocyte chemotactic protein (MCP-1/CCL2)
D) Delayed hypersensitivity - Mycobacterium tuberculosis, Mycobacterium leprae, Pneumocystis carinii, Leishmania species, and herpes simplex virus

A

C) L-3 and GM-CSF induce hematopoiesis; monocyte chemotactic protein (MCP-1/CCL2)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which of the following conditions is a classic example of delayed hypersensitivity mediated by Type IV hypersensitivity?

A) Tuberculosis
B) Robert Koch 1890 - Mycobacterium Tuberculosis
C) Granulomas
D) Delayed hypersensitivity - Mycobacterium tuberculosis, Mycobacterium leprae, Pneumocystis carinii, Leishmania species, and herpes simplex virus

A

D) Delayed hypersensitivity - Mycobacterium tuberculosis, Mycobacterium leprae, Pneumocystis carinii, Leishmania species, and herpes simplex virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which of the following diseases is associated with Type IV hypersensitivity?

A) Influenza
B) Chickenpox
C) Tuberculosis
D) Measles

A

C) Tuberculosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which of the following antigens can trigger Type 4 hypersensitivity reactions?

A. Intracellular pathogens - bacteria, fungi, parasites, or viruses.
B. Allergens such as pollen and dust mites.
C. Antibodies produced against a previous infection.
D. Ingested food allergens.

A

A. Intracellular pathogens - bacteria, fungi, parasites, or viruses.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which of the following antigens can trigger a Type 4 hypersensitivity reaction?

A. Viruses and bacteria
B. Contact antigens like poison ivy, nickel salts, and components of hair dyes
C. Allergens like pollen and dust mites
D. Food allergens such as peanuts and shellfis

A

B. Contact antigens like poison ivy, nickel salts, and components of hair dyes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which of the following best describes the antigens that can trigger Type 4 hypersensitivity reactions?

A) Antigens associated with respiratory allergies
B) Antigens that are common causes of food allergies
C) Contact antigens, often associated with skin disorders
D) Antigens found in blood, leading to transfusion reactions

A

C) Contact antigens, often associated with skin disorders

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which of the following is an example of an antigen that can trigger a Type 4 hypersensitivity reaction?

A) Pollen
B) Latex
C) Food allergens
D) Vaccines

A

B) Latex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which of the following is considered the gold standard for testing contact antigens that can trigger a Type 4 hypersensitivity reaction?

A) ELISA test
B) Skin prick test
C) Patch test
D) PCR assay

A

C) Patch test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which diagnostic method is commonly used to detect delayed hypersensitivity reactions in tuberculosis?

A. Skin testing
B. Blood culture
C. Chest X-ray
D. Urine analysis

A

A. Skin testing

17
Q

Which of the following antigens are commonly used in skin testing?

A) Influenza virus particles
B) Candida albicans, tetanus toxoid, Streptococcus
bacteria, and fungal antigens such as trichophyton and histoplasmin
C) Bacterial DNA
D) Food allergens

A

B) Candida albicans, tetanus toxoid, Streptococcus
bacteria, and fungal antigens such as trichophyton and histoplasmin

18
Q

What does the Tuberculin skin test use as its antigen extract?

A) Mycobacterium tuberculosis bacteria
B) Purified protein derivative (PPD)
C) Cell membrane proteins
D) Lipid-soluble molecules

A

B) Purified protein derivative (PPD)

19
Q

What does a positive result in a Tuberculin skin test indicate?

A) The individual has an active tuberculosis infection.
B) The individual has never been exposed to M. tuberculosis.
C) The individual has been vaccinated against tuberculosis.
D) The individual has previously been exposed to M. tuberculosis or a related organism, but it does not necessarily mean that he or she has an active tuberculosis infection.

A

D) The individual has previously been exposed to M. tuberculosis or a related organism, but it does not necessarily mean that he or she has an active tuberculosis infection.

20
Q

What type of response is generally expected in individuals who have received the BCG vaccine when they undergo a Tuberculin skin test?

A) Positive reaction
B) Negative reaction
C) No visible reaction
D) Variable reaction

A

A) Positive reaction

HYPERSENSITIVITY BOOK (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions