Type 2 Diabetes Flashcards
Type 2 diabetes
Most prevalent 90-95%
What are the many risk factors of type 2 diabetes (3)
Greater prevalence in ethnic group
Obese
Advanced age
Family history
What is the etiology of diabetes 2?
(3) after the main
Pancreas contained to provide some endogenous insulin however
- not enough insulin/produced
- insulin not used
- cells became resistant to circulating insulin
Metabolic and gene abnormalities play a huge role in developing diabetes type 2
What is the number one role?
Insulin resistance
Why is insulin resistance a major factor in creating diabetes 2 ? (3)
Decreased insulin production by pancreas
Inappropriate hepatic glucose production
Altered production of hormones and cytokines by adipose tissue
( adipokines )
Extra notes
When insulin is not properly used, the entry of glucose into the cell is impeded, causing hyperglycemia
In early stages of insulin resistance, the pancreas responds to high glucose levels by producing more insulin
Causing a state of hyperinsulinemia and hyperglycemia
Metabolic syndrome also plays a huge role in getting Diabetes type 2 why? (5)
Having 3 out of 5 of these you will have metabolic syndrome
Increase glucose levels
Abdominal obesity
High blood pressure
High level of trigs
Decreased levels of HDL
Type 2 diabetes has a what type of symptoms ? ___onset
___ may go many years without being detected
Gradual onset
Hyperglycemia
Hyperglycemia is often discovered how? (2)
Routine glucose testing
Hemoglobin AIC
At the time of the diagnosis
About 50-80% of B cells are not longer what ?
Which means that the patient has had diabetes for more than how many years??
Secreting insulin
6.5
What are the clinical manifestations of type 2 diabetes? (6)
THEY WILL HAVE NONSPECIFIC SYMPTOMS !!
Fatigue
Recurrent infection
Recurrent vaginal yeast
Prolonged wound healing
Visual problems
3 ps
