Hypothyroidism Flashcards
What is hypothyroidism (3)?
Deficiency of thyroid hormone
Slow metabolic rate
More common in women
There are two types of hypothyroidism what are they each?
Primary and secondary
What is primary hypothyroidism?
Caused by destruction of thyroid tissue or defective hormone synthesis
What is secondary hypothyroidism?
Caused by pituitary or hypothalamic dysfunction
What are the 5 things that causes hypothyroidism?
Iodine deficiency
Atrophy of the gland
Treatment for hyperthyroidism
Drugs ( amiodarone & lithium )
Creatinism if occurs in infancy
Notes
Most common cause of primary hypothyroidism is atrophy of the thyroid gland
- results from hashimoto thyroiditis or Graves’ disease
Notes
Clinical manifestation
Systemic effects characterized by slowing of body process
Manifestations variable
Slow onset!!
Notes
Cardiovascular clinical manifestations
- Decrease cardiac contractility & output
- Angina, heart failure, MI
- Anemia
( cobalamin, iron, folate deficient )
- Serum increase cholesterol & trigs
Decrease cardiac contractility & output
Angina, heart failure, MI
Anemia
( cobalamin, iron, folate deficient )
Serum increase cholesterol & trigs
Notes
Respiratory clinical manifestations
- Low exercise tolerance
- Shortness of breath on exertion
Low exercise tolerance
Shortness of breath on exertion
Notes
Neurologic systemic clinical manifestations
- Fatigue & lethargy
- Personality & mood changes
- Impaired memory
- Slow speech
- Decrease initiative & somnolence
- Depressed
Fatigue & lethargy
Personality & mood changes
Impaired memory
Slow speech
Decrease initiative & somnolence
Depressed
Notes
Gastrointestinal system
- decreased appetite !!
- nausea & vomiting
- weight gain!!
- constipation
- distended abdomen
- enlarged scaly tongue !!
- celiac disease
Notes
Integumentary system
- dry, think, in elastic, cold skin
- thick brittle nails
- dry, sparse coarse hair !!
- poor tugor or mucosa
- generalized interstitial edema
- puffy face !!
- decreased sweating
- pallor
Notes
Musculoskeletal system
- fatigue, weakness
- muscular aches and pains !!
- slow movements
- arthralgia !!
Notes
Reproductive systemic
- prolonged menstrual periods
- amenorrhea!!
- decreased libido
- infertility
Notes
Other clinical manifestation
- increased susceptibility to infection
- increased sensitivity to opioids, barbiturates, anesthesia
- intolerance to cold
- decreased hearing
- sleepiness
- goiter