TxWes Guide Antiemetics/Nonopioids Flashcards
ANTIEMETICS
Dose, Onset, Duration:
Droperidol
Inapsine
0.625mg⎪O: 1-5min⎪D: 2-3hrs
ANTIEMETICS
Dose, Onset, Duration:
Promethazine
Phenergan
6.25 - 25 mg⎪O: 1-5mins⎪D: 4-6hrs
ANTIEMETICS
Dose, Onset, Duration:
Ondansetron
Zofran
4mg⎪O: 10mins⎪D: 4-9hrs
ANTIEMETICS
Dose, Onset, Duration:
Dexamethasone
Decadron
4mg⎪O: 10-30mins⎪D: 2-10hrs
ANTIEMETICS
Dose, Onset, Duration:
Metoclopramide
Reglan
10-20mg⎪O: 10mins⎪D: 2hrs
ANTIEMETICS
Dose, Onset, Duration:
Scopolamine
Patch⎪O: 2-4hrs⎪D: 72hrs
Non-hairy area - dont touch eyes after handling –> can cause mydriasis.
ANTIEMETICS
Dose, Onset, Duration:
Propofol
Diprivan
Antiemetic Dose
10-15mg IV followed by 10mcg/kg/min
List some PONV risk factors.
Female, <40yrs, Hx of PONV or Motion Sickness, vertigo, non-smokers
Surgeries: Laparotomy, Laparoscopy, Major Breast, Strabismus, Intraocular, Middle Ear, Tonsils, Adenoids, Neuro (intracranial), Gynecologic, Testicular, Scrotum, Kidney stones
If I have 0 PONV risk factors, what is the chance I will have PONV?
10%
This requires NO prophylactic drugs.
If I have 3 PONV risk factors, what is the chance I will have PONV?
What drugs will you treat your patient with?
> 60% chance.
Give at least 3 treament drugs: 5HT blocker, steroid, propofol + TIVA??
My patient requires 2 pre-treatment drugs for PONV; I gave zofran and decadron before her surgery.
How many risk factors do you think she has?
What are her chances of developing PONV based on this info?
2 risk factors = 40% chance of developing PONV
My chance of PONV is 20%.
How many risk factors do I have?
What drug(s) will you give me?
I have 1 risk factor and you should give me a 5HT-blocker like zofran :)
NON OPIOID ANALGESICS
Dose & daily MAX dose.
Acetaminophen
Ofirmev
1000mg q 4-6hr
MAX: 3-4g qd
NON OPIOID ANALGESICS
Dose & daily MAX dose.
Ketorlac
Toradol
15-30mg q6h
Max: 60-120mg qd
NON OPIOID ANALGESICS
1x Dose & daily MAX dose.
Ibuprofen
Caldor
200-800mg q6h
Max: 3200mg qd