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.Drug Doses/Info > Dosages NMBs, LAs, Pressors > Flashcards

Dosages NMBs, LAs, Pressors Flashcards

1
Q

What is the dose of Succinylcholine?
Onset:
Duration:
Metabolism:

A

Succinylcholine (Anectine)
Dose: 1 mg/kg IV
Onset: 30-60 seconds
Duration: 3-5 minutes
Metabolism: pseudocholinesterase

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2
Q

Dantrolene
Dose:
Metabolism:

A

Dantrolene (Ryanodex)
Dose: 2mg/kg IV
Repeat doses until symptoms subside or 10mg/kg IV
Metabolism: Hepatic

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3
Q

What is the dose of SCh for MG patients?

A

1.5-2.0 mg/kg
(increased d/t resistance)

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4
Q

For a patient with burns needing intubation, how can we offset the resistance to non-depolarizing blockers the burn causes?

A

1.2 mg/kg dose of Rocuronium

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5
Q

Pancuronium
Dose:
Onset:
Duration:
Metabolism:

A

Pancuronium (Pavulon)
- Dose: 0.1mg/kg;
- Onset: 3-5 minutes;
- Duration: 60-90 minutes
Metabolism: Hepatic
Excretion: 80% unchanged in Urine

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6
Q

Vecuronium
Dose:
Onset:
Duration:
Metabolism:

A

Vecuronium (Norcuron)
- Intubating Dose: 0.1 mg/kg
- Onset: 3-5 minutes
- Duration: 20-35 minutes
Metabolism: 70% Hepatic
Excretion: 30% unchanged in Urine

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7
Q

Rocuronium
Normal Dose:
Onset:
Duration:
Metabolism:
Excretion:

A

Rocuronium (Zemuron)
* Dose: 0.6 mg/kg
* Onset: 3-5 minutes
* Duration: 20-35 minutes
Metabolism: Hepatic
Excretion: Bile, 10-30% Renal

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8
Q

Rocuronium
RSI Dose:
Onset:
Duration:
Metabolism:
Excretion:

A

Rocuronium (Zemuron)
- Dose: 1.2 mg/kg
- Onset: 1-2 minutes
- Duration: 60-90 minutes
Metabolism: Hepatic
Excretion: Bile, 10-30% Renal

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9
Q

Cisatracurium
Dose:
Onset:
Duration:
Metabolism:

A

Cisatracurium (Nimbex)
* Intubating Dose: 0.1 mg/kg;
* Onset: 3-5 minutes;
* Duration of action: 20-35 minutes
Metabolism: Hoffman elim & plasma cholinesterase

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10
Q

Mivacurium
Dose:
Onset:
Duration:
Metabolism:

A

Mivacurium (Mivacron)
* Intubating Dose: 0.15 mg/kg;
* Onset: 2-3 minutes (Conditions less desirable);
* Duration: 12-20 minutes
Metabolism: plasma cholinesterase

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11
Q

Neostigmine
Dose:
Max:
Onset:
Duration:

A

Neostigmine (prostigmine)
Dose: 40 - 70 mcg/kg
Max: 5mg
Onset: 5-10 min
Duration: 60 min

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12
Q

Edrophonium
Dose:
Onset:
Duration:

A

Edrophonium (Tensilon)
Dose: 0.5 - 1 mg/kg
Onset: 1-2 min
Duration: 5-15min

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13
Q

What is the dose of Atropine?

A

7 - 10 mcg/kg

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14
Q

What is the Sugammadex dose for a moderate block?
Onset:
Duration:
Elimination:

A

Sugammadex (Bridion)
2 mg/kg
Onset: 1-4 min
Duration: 1.5 - 3 hours
Elimination: Urine

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15
Q

What is the Sugammadex dose for a deep block?

A

4 mg/kg

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16
Q

What is the sugammadex dose for an extreme block?

A

8 - 16 mg/kg

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17
Q

What drug and dose would be a good choice for a recurarizing patient in the PACU?
Why might this be a good choice?

A
  • Neostigmine 0.05 mg/kg IV (40-70mcg/kg)
  • Longer duration of action (60min)
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18
Q

What is the dose and max for glycopyrrolate?

A

7 - 15 mcg/kg

1mg maximum

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19
Q

MAGA: What is the intra-op infusion dose of lidocaine?

A

1 mg/kg over an hour

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20
Q

What is the IV dose of Lidocaine? (bolus and drip)

A
  • 1 to 2 mg/kg IV (initial bolus) over 2 - 4 min.
  • 1 to 2 mg/kg/hour (drip)
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21
Q

What is Lidocaine’s max infiltration dose? (with and without Epi)

A
  • 300 mg plain
  • 500 mg with Epi
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22
Q

What is the max dose of prilocaine?

A

600 mgs

23
Q

What is the treatment and dose for methemoglobinemia secondary to prilocaine overdose?

A

Methylene Blue

  • 1 to 2 mg/kg IV over 5 mins (initial dose)
  • Total dose not to exceed 8 mg/kg
24
Q

Benzocaine
Onset:
Duration:
Dose:

A

onset: rapid

duration: 30-60 min

Dose: 200-300 mg = 20% spray

25
Q

Lidocaine max single dose

Infiltration:
Topical:
Epidural:
Spinal:
PNB:

A
  • Infiltration: 300mg or 500mg with Epi
  • Topical: 300 mg
  • Epidural: 300mg or 500mg with Epi
  • Spinal: 100mg
  • PNB: 300mg or 500mg with Epi
26
Q

Prilocaine Recommended Max Single Dose for infiltration/IVRA/PNB/Epidural?

A

600 mg

27
Q

Bupivacaine Recommended Max Single Dose

Bupivacaine Recommended Max Single Dose with/Epi

Bupivacaine Recommended Max Single Dose for Spinal

A

175 mg

225 mg w/ Epi

Spinal max: 20 mg

28
Q

Eutectic Mixture of LA (EMLA) contains what two local anesthetics?
Dose:
Onset:

A

Lidocaine 2.5% + Prilocaine 2.5% = 5% LA
Dose: 1 to 2 g/ 10 cm² area
Onset: 45 mins

29
Q

What is the dose of bupivacaine for the scenario below?

5 ft tall patient = _____mL of ____% Bupivacaine
+ ______ mL for every inch above…. 2 cc total ( 1½ hours to 2 hours)

A

1 mL of 0.75% Bupivacaine
0.1 mL

For someone who is 5’5”, you will give 1.5 mL of 0.75% bupivacaine for a SAB.

30
Q

What makes up the tumescent solution?

A
  • Diluted Lidocaine (0.05% to 0.1%)
  • Epinephrine 1:100,000
31
Q

What is the dose for Regional Anesthesia Lidocaine with Epi?

A

7 mg/kg

32
Q

Highly diluted Lidocaine with Epi Tumescent dose.

A

35 to 55 mg/kg

33
Q

What is the bolus dose of Lipid Emulsion?

A

1.5 mL/kg of 20% lipid emulsion

34
Q

What is the infusion dose of lipid emulsion?
How long should it be given?

A

0.25 mL/kg/minute for at least 10 minutes

35
Q

What is the max total dose for lipid emulsion that should be given?

A

8 mL/kg

36
Q

If cardiac arrest occurs with LAST syndrome, how should our epinephrine dosing change?

A

Small doses (10mcg - 100mcg boluses) are preferred with LAST ACLS.

37
Q

What is the treatment for methemoglobinemia? What is the max dosage?

A

Methylene blue 1mg/kg over 5min

max: 8 mg/kg

38
Q

What is the dose for Atenolol?

A

5mg q10min IV

39
Q

What is the dose of metoprolol?

A

1mg q5min (Given in 5mg “blocks”)

40
Q

What is the initial dose for esmolol?

A

20-30mg IV

41
Q

What is the normal dosing of phenylephrine?

A

50-100mcg IV push

42
Q

What is the dose for labetalol? How long would it take to see max effect from IV dose?

A

2.5 - 5mg IV; 10mg max
IV max effect 5-10 min

43
Q

What is the IV push dose of epinephrine?
How long does it last?

A
  • 2-8mcg IVpush
  • 1-5 min
44
Q

What is the infusion dose of epinephrine for β2 effects?

A

1-2 mcg/min

45
Q

What is the infusion dose of epinephrine for β1 effects?

A

4 mcg/min

46
Q

What is the infusion dose of epinephrine for predominantly α effects?

A

10-20 mcg/min

47
Q

Which SNS agonist can be given IM? What dose?
Why would this be done?

A
  • Ephedrine IM 50mg
  • Long lasting increase in BP for OB patients.
48
Q

What is the dose of Nitroprusside?

A

Initial: 0.3 mcg/kg/min
Tritrate slowly to 2 mcg/kg/min

49
Q

What is the nitroglycerin dose?

A

Initial: 5 - 10 mcg/min

50
Q

What is the initial dose of hydralazine?

A

2.5mg IV

51
Q

What is the dose of nicardipine?

A

5mg/hr (↑2.5mg x4hr)
max 15mg/hr

52
Q

What is the single IV push dose for ephedrine?

A

5-10mg IV

53
Q

What is the single IV dose for vasopressin?

A

1-2 units IV

.Drug Doses/Info (22 decks)

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