Tx of Grave's Disease

Question 1

what are the treatments for grave’s disease?

Answer 1

1) anti-thyroid drugs
2) radioactive iodine therapy
3) surgery

Question 2

give an example of an antithyroid drug?

Answer 2

tapazole = inhibits synthesis of TH

Question 3

explain radioactive iodine therapy

Answer 3

• T3 and T4 need iodine to be synthesized
• when it binds to thyroid cells, it emits radiation and forms free radicals
• given in a low dose according to target amount of cells you want to have left

Question 4

what is the goal of radioactive iodine therapy?

Answer 4

decrease overproduction without eradicating T3/T4

Question 5

explain surgery

Answer 5

you would remove the thyroid gland, or a portion of it

Question 6

what can happen with secretion in relation to these treatments?

Answer 6

you can easily go from hypersecretion to hyposecretion