Turgeon (CHAPTER REVIEW)

Question 1

1-5. Match the following terms to their appropriate definitions or
descriptions. (Use each answer only once.)
1. _____ Immune system
2. _____ Lymphocytes
3. _____ Cooperative interaction
4. _____ Nonspecific immune elements
5. _____ Autoimmune disorder

a. T and B types
b. Specific cellular elements, cell products, and nonlymphoid
elements
c. Mononuclear phagocytes
d. Condition in which the body’s own tissues are attacked as if they were foreign
e. Can protect against or be manipulated to treat disease

Answer 1

1. E
2. A
3. B
4. C
5. D

Question 2

6. The first line of defense in protecting the body from infection includes all the following components except:

a. Unbroken skin
b. Normal microbial fora
c. Phagocytic leukocytes
d. Secretions such as mucus

Answer 2

c. Phagocytic leukocytes

Question 3

7. Natural immunity is characterized as being:

a. Innate or inborn
b. Able to recognize exogenous or endogenous agents specifically
c. Able to eliminate exogenous or endogenous agents selectively
d. Part of the first line of body defenses against microbial organisms

Answer 3

a. Innate or inborn

Question 4

10. Another term for adaptive immunity is:

a. Antigenic immunity
b. Acquired immunity
c. Lymphocyte reactive immunity
d. Phagocytosis

Answer 4

b. Acquired immunity

Question 5

11. Humoral components of the adaptive immune system include:

a. T lymphocytes
b. B lymphocytes
c. Antibodies
d. Saliva

Answer 5

c. Antibodies

Question 6

12-23. Complete the table below, choosing from the following answers:

Possible answers for questions 12-15:

a. Infusion of serum of plasma
b. Transfer in vivo or by colostrum
c. Vaccination
d. Infection

Type Mode of Acquisition
Active natural 12. _____
Artificial active 13. _____
Passive natural 14. _____
Artificial passive 15. _____

Answer 6

12. D
13. C
14. B
15. A

Question 7

Possible answers for questions 16-19:

a. Yes
b. No

Antibody Produced by Host
Active natural 16. _____
Artificial active 17. _____
Passive natural 18. _____
Artificial passive 19. _____

Answer 7

16. A
17. A
18. B
19. B

Question 8

Possible answers for questions 20-23:
a. Short
b. Long

Type Duration of Response
Active natural 20. _____
Artificial active 21. _____
Passive natural 22. _____
Artificial passive 23. _____

Answer 8

20. B
21. B
22. A
23. A

Question 9

1. A synonym for an antigenic determinant is:

a. Immunogen
b. Epitope
c. Binding site
d. Polysaccharide

Answer 9

b. Epitope

Question 10

2. Genetically different individuals of the same species are referred to as:

a. Allogenic
b. Heterogenic
c. Autogenic
d. Isogenic

Answer 10

a. Allogenic

Question 11

3. Antigenic substances can be composed of:

a. large polysaccharides
b. Proteins
c. Glycoproteins
d. All of the above

Answer 11

d. All of the above

Question 12

4. Which of the following characteristics of an antigen is the least important?

a. Foreignness
b. Degradability
c. Molecular weight
d. Presence of large repeating polymers

Answer 12

d. Presence of large repeating polymers

Question 13

5. The chemical composition of an antibody is:

a. Protein
b. Lipid
c. Carbohydrate
d. Any of the above

Answer 13

a. Protein

Question 14

6-10. Match the following characteristics with the appropriate antibody class (use an answer only once).

6. _____ IgM
7. _____ IgG
8. _____ IgA
9. _____ IgE
10. _____ IgD

a. Highest in plasma or serum concentration in normal
individuals
b. Shortest half-life
c. 19S
d. Can exist as a dimer
e. No known subclasses

Answer 14

6. _____ IgM C
7. _____ IgG A
8. _____ IgA D
9. _____ IgE B
10. _____ IgD E

Question 15

16-18. Match each of the following antigenic determinant terms with its
appropriate definition. Basic Immunologic Mechanisms

16. _____ Isotype
17. _____ Allotype
18. _____ Idiotype

a. Found on the immunoglobulins of some, but not all, animals of a species
b. Dominant type found on immunoglobulins of all animals of a species
c. Individual determinants characteristic of each antibody

Answer 15

16. _____ Isotype B
17. _____ Allotype A
18. _____ Idiotype C

Question 15

11-15. Match the following characteristics with the appropriate antibody (use an answer only once).

11. _____ IgG
12. _____ IgM
13. _____ IgA
14. _____ IgD
15. _____ IgE

a. Predominant immunoglobulin in secretions
b. Increased in infectious diseases, collagen disorders, and hematologic disorders
c. Mediates some types of hypersensitivity reactions
d. Primarily a cell membrane immunoglobulin
e. Produced early in an immune response

Answer 15

11. _____ IgG B
12. _____ IgM E
13. _____ IgA A
14. _____ IgD D
15. _____ IgE C

Question 16

19-22. Arrange the sequence of events of a typical antibody response.

19. _____
20. _____
21. _____
22. _____

a. Plateau
b. Lag phase
c. Log phase
d. Decline

Answer 16

19. _____ B
20. _____ C
21. _____ A
22. _____ D

Question 17

23. Which of the following statements is false about an anamnestic response versus a primary response?

a. Has a shorter lag phase
b. Has a longer plateau
c. Antibodies decline more gradually.
d. IgM antibodies predominate.

Answer 17

d. IgM antibodies predominate.