Tumour pathology: formative review Flashcards
1
Q
What does a higher tumour grade mean
A
Poorer prognosis
2
Q
is PSA a specific. screening tool for prostate cancer
A
no
3
Q
What do hepatocellular carcinomas and germ cell tumours produce
A
Alpha-fetoprotein
4
Q
What do Burkitt;s lymphoma and neuroblastoma produce
A
Harbour alterations in the MYC oncogene
5
Q
What control the G1 phase of cell cycle
A
cyclin D cdk4/6
6
Q
What controls the G1-s phase of the cell cycle
A
cyclinE cdk2
7
Q
What controls the S phase of the cell cycle
A
Cyclin A cdk2/1
8
Q
What controls the M phase of the cell cycle
A
Cyclin B and cdk1
9
Q
what pathogen causes stomach cancer
A
H.pylori
10
Q
What chemical causes bladder cancer
A
VInyl cancer
11
Q
What causes nasopharyngeal cancer
A
EBV
12
Q
What causes Kaposi’s cancer
A
HHV8/HIV
13
Q
What causes mesothelioma
A
asbestos
