Tumour Markers

Question 1

What is the tumour marker for ovarian cancer?

Answer 1

CA-125

Question 2

What is the tumour marker for hepatocellular carcinoma?

Answer 2

Alpha felt protein

Question 3

What cancers is alpha detox protein a marker of?

Answer 3

Hepatocellular

Germ cell/testicular

Question 4

What is the tumour marker for pancreatic cancer?

Answer 4

CA 19-9

Question 5

What is the tumour marker for colorectal cancer?

Answer 5

CEA - carcinoembryonic antigen

Question 6

What is a marker of a B cell proliferative disorder?

Answer 6

Paraproteins

Question 7

What is a tumour marker of breast cancer?

Answer 7

Ca 15-3

Question 8

What is the tumour marker for germ cell/testicular cancer?

Answer 8

Beta-HCG

Question 9

Define tumour markers

Answer 9

Specific molecules that may be found in higher concentrations in the serum and other tissues in patients with certain cancer.

Question 10

What is the main value of tumour markers?

Answer 10

Monitoring the course of an illness, treatment effectiveness and detecting cancer reoccurrence.

Question 11

What are the cautions to be had regarding use of tumour markers.

Answer 11

Absence doesn’t = no disease

Can associated with multiple diseases, including benign conditions (not specific or diagnostic)

Question 12

What are the causes of a raised PSA other than prostate Ca or BPH?

Answer 12

Urine infection
DRE
Biopsy
Rigorous exercise 
Recent ejaculation