Tumour Biology plus grading/staging

Question 1

What makes a benign tumour diff to malignat?

Answer 1

Benign: differntiated; expansile growth
Malignant: metastatses; less differentiated; infiltrative growth

Question 2

What is micropscopic analysis to show malignancy?

Answer 2

Disorganised; invasion

Increased staining; increased nuclear size; varaition of nuclear shape; mitoses; decreased cell cohesion