Tumor Suppressor Gene Or Oncogene? Flashcards

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1
Q

Alk

A

Oncogene

Lung adenoca

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2
Q

Bcr Abl

A

Oncogene

CML ALL

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3
Q

BCL 2

A

Oncogene

Follicular and diffuse large b cell lymphoma

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4
Q

BRAF

A

Oncogene

Melanoma, non hodgkin lymphoma, papillary thyroid ca

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5
Q

C-KIT

A

Oncogene

GIST

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6
Q

C- MYC

A

Oncogene

Burkitt lymphoma

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7
Q

Her2Neu ( c erbB2)

A

Oncogene

Breast and Gastric ca

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8
Q

Jak2

A

Oncogene

Chronic myeloproliferative disorders

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9
Q

KRAS

A

Oncogene

Colon ca, lung ca, pancreatic ca

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10
Q

MYCL1

A

Oncogene

Lung tumor

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11
Q

MYCN

A

Oncogene

Neuroblastoma

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12
Q

RET

A

Oncogene

MEN 2A and 2B, medullary thyroid ca

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13
Q

PDGFB

A

Oncogene

Astocytoma

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14
Q

CCN1

A

Oncogene

Mantle cell lymphoma

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15
Q

CDK4

A

Oncogene

Melanima

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16
Q

APC

A

TSG

Colorectal ca

17
Q

BRCA1/2

A

TSG

Breast ovarian pancreatic

18
Q

CDKN2a

A

TSG

Melanoma pancreatic ca

19
Q

DCC

A

TSG

Colon ca

20
Q

DPC4/SMAD4

A

Pancreatic ca

21
Q

MEN1

A

TSG

MEN1

22
Q

NF1

A

TSG

23
Q

NF2

A

TSG

24
Q

PTEN

A

TSG

Breast prostate endometrial

25
Q

Rb

A

TSG

Li fraumenni

26
Q

TSC1

A

TSG

Tuberous sclerosis

27
Q

TSC2

A

TSG

Tuberous sclerosis

28
Q

VHL

A

TSG

29
Q

WT1

A

TSG