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My USMLE > Therapeutic Antibodies > Flashcards

Therapeutic Antibodies Flashcards

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USMLE® Step 1 flashcards
1
Q

Alemtuzumab

A

CD 52; CLL, MS

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2
Q

Bevacizumab

A

VEGF (Colorectal ca; Renal cell ca; Non small cell lung ca)

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3
Q

Cetuximab

A

EGFR (Stage IV colorectal ca; head and neck ca)

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4
Q

Rituximab

A

CD 20 (Bcell nonHodgkin lymphoma, CLL, Rheumatoid arthritis, ITP

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5
Q

Trastuzumab

A

HER2/neu (Breast ca, gastric ca)

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6
Q

Adalimumab, Certolizumab, Golimumab, Infliximab

A

Soluble TNF a (IBD, RA, ankylosing spondylitis, psoriasis)

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7
Q

Daclizumab

A

CD25 (Relapsing multiple sclerosi)

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8
Q

Eculizumab

A

Complement protein C5 (PNH)

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9
Q

Natalizumab

A

a4 integrin (Multiple sclerosis, Crohn disease)

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10
Q

Ustekinumab

A

IL 12/ IL 23 (Psoriasis, psoriatic arthritis)

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11
Q

Abciximab

A

Platelet glycoprotein IIB/IIIA

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12
Q

Denosumab

A

RANKL (osteoporosis)

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13
Q

Digoxin immune Fab

A

Antidote for digoxin toxicity

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14
Q

Omalizumab

A

IgE (refractory allergic asthma)

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15
Q

Palivizumab

A

RSV F protein (RSV prophylaxis for high risk infants)

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16
Q

Ranibizumab, Bevacizumab

A

VEGF (Neovascular age related macular degenration; proliferative diabetic retinopathy and macular edema)

My USMLE (11 decks)

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