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My USMLE > Antibodies > Flashcards

Antibodies Flashcards

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USMLE® Step 1 flashcards
1
Q

anti- dsDNA

A

SLE

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2
Q

ANA

A

SLE, RA, mixes connective tissue disease

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3
Q

anti mitochondrial antibodies

A

primary biliary cirrhosis

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4
Q

anti smooth muscle antibody (ASMA)

A

autoimmune hepatitis

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5
Q

pANCA perinuclear antineutrophil cytoplasmic antibody

A

ulcerative colitis and primary sclerosing cholangitis

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6
Q

HLA DR4

A

DM type 1

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7
Q

anti Histone

A

drug induced SLE

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8
Q

HLA A3

A

hemochromatosis defective iron excretion

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9
Q

anti CCP

A

rheumatoid arthritis

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10
Q

HLA B27

A

Ankylosing spondylitia; Reiter syndrome; Acute anterior uveitis

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11
Q

HLA B8

A

Hyperthyroidism (Grave’s Disease)

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12
Q

HLA Cw6

A

Psoriasis vulgaris

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13
Q

HLA DR2

A

Multiple sclerosis; Goodpasteur syndrome

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14
Q

Anti Ach receptor

A

Myasthenia Gravis

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15
Q

Anti- glomerular basement membrane

A

Goodpasture syndrome

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16
Q

Anti- B2 glycoprotein

A

Antiphospholipid syndrome

17
Q

Anticardiolipin; lupus anticoagulant

A

SLE, Antiphospholipid syndrome

18
Q

Anticentromere

A

Limited Scleroderma (CREST syndrome)

19
Q

Antidesmoglein (antidesmosome)

A

Pemphigus vulgaris

20
Q

Anti Glutamic acid decarboxylase

A

Type 1 DM

21
Q

Anti hemidesmosome

A

Bullous pemphigoid

22
Q

Antisynthetase (anti- Jo); anti SRP, antihelicase (antiMi 2)

A

Polymyositis, dermatomyositis

23
Q

Antimicrosomal, antithyroglobulin, anti- thyroid peroxidase

A

Hashimito thyroiditis

24
Q

Antimitochondrial

A

1 biliary cirrhosis

25
Q

Antiparietal cell, anti- intrinsic factor

A

Pernicious anemia

26
Q

Antiphospholipase A2 receptor

A

1 membranous nephropathy

27
Q

Anti Scl 70 (anti- DNA topoisomerase I)

A

Scleroderma (diffuse)

28
Q

Anti smooth muscle

A

Autoimmune hepatitis type I

29
Q

Anti SSA and Anti SSB (anti Ro, anti La)

A

Sjogren syndrome

30
Q

Anti TSH receptor

A

Graves Disease

31
Q

Anti presynaptic voltage gated calcium channel

A

Lamber eaton myasthenic syndrome

32
Q

IgA anti endomysial, IgA anti - tissue transglutaminase

A

Celiac disease

33
Q

MPO ANCA/ p ANCA

A

Microscopic polyangiitis,eosinophilic granulomatosis with polyangiitis (Churg Strauss syndrome), ulcerative colitis

34
Q

PR3 ANCA/ c ANCA

A

Granulomatosis with polyangiitis (Wegener)

35
Q

Rheumatoid Factor (IgM antibody against IgG Fc region), anti CCP

A

rheumatoid arthritis

36
Q

Antinuclear antibody

A

nonspecific screening antibody, SLE

37
Q

Anti dsDNA, anti- Smith

A

SLE

38
Q

Anti- U1 RNP (Ribonucleoprotein)

A

Mixed connective tissue disease

My USMLE (11 decks)

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