Antibodies Flashcards

1
Q

anti- dsDNA

A

SLE

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2
Q

ANA

A

SLE, RA, mixes connective tissue disease

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3
Q

anti mitochondrial antibodies

A

primary biliary cirrhosis

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4
Q

anti smooth muscle antibody (ASMA)

A

autoimmune hepatitis

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5
Q

pANCA perinuclear antineutrophil cytoplasmic antibody

A

ulcerative colitis and primary sclerosing cholangitis

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6
Q

HLA DR4

A

DM type 1

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7
Q

anti Histone

A

drug induced SLE

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8
Q

HLA A3

A

hemochromatosis defective iron excretion

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9
Q

anti CCP

A

rheumatoid arthritis

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10
Q

HLA B27

A

Ankylosing spondylitia; Reiter syndrome; Acute anterior uveitis

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11
Q

HLA B8

A

Hyperthyroidism (Grave’s Disease)

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12
Q

HLA Cw6

A

Psoriasis vulgaris

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13
Q

HLA DR2

A

Multiple sclerosis; Goodpasteur syndrome

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14
Q

Anti Ach receptor

A

Myasthenia Gravis

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15
Q

Anti- glomerular basement membrane

A

Goodpasture syndrome

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16
Q

Anti- B2 glycoprotein

A

Antiphospholipid syndrome

17
Q

Anticardiolipin; lupus anticoagulant

A

SLE, Antiphospholipid syndrome

18
Q

Anticentromere

A

Limited Scleroderma (CREST syndrome)

19
Q

Antidesmoglein (antidesmosome)

A

Pemphigus vulgaris

20
Q

Anti Glutamic acid decarboxylase

21
Q

Anti hemidesmosome

A

Bullous pemphigoid

22
Q

Antisynthetase (anti- Jo); anti SRP, antihelicase (antiMi 2)

A

Polymyositis, dermatomyositis

23
Q

Antimicrosomal, antithyroglobulin, anti- thyroid peroxidase

A

Hashimito thyroiditis

24
Q

Antimitochondrial

A

1 biliary cirrhosis

25
Antiparietal cell, anti- intrinsic factor
Pernicious anemia
26
Antiphospholipase A2 receptor
1 membranous nephropathy
27
Anti Scl 70 (anti- DNA topoisomerase I)
Scleroderma (diffuse)
28
Anti smooth muscle
Autoimmune hepatitis type I
29
Anti SSA and Anti SSB (anti Ro, anti La)
Sjogren syndrome
30
Anti TSH receptor
Graves Disease
31
Anti presynaptic voltage gated calcium channel
Lamber eaton myasthenic syndrome
32
IgA anti endomysial, IgA anti - tissue transglutaminase
Celiac disease
33
MPO ANCA/ p ANCA
Microscopic polyangiitis,eosinophilic granulomatosis with polyangiitis (Churg Strauss syndrome), ulcerative colitis
34
PR3 ANCA/ c ANCA
Granulomatosis with polyangiitis (Wegener)
35
Rheumatoid Factor (IgM antibody against IgG Fc region), anti CCP
rheumatoid arthritis
36
Antinuclear antibody
nonspecific screening antibody, SLE
37
Anti dsDNA, anti- Smith
SLE
38
Anti- U1 RNP (Ribonucleoprotein)
Mixed connective tissue disease