Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pathology > Tumor markers and oncogenic microbes > Flashcards

Tumor markers and oncogenic microbes Flashcards

1
Q

Purpose of tumor markers?

A

Monitor tumor recurrence, response to therapy

*Biopsy makes the definitive diagnosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Alkaline phosphatase

A

Metastases to bone or liver
Pagest disease of bone
Seminoma (placental ALP)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

AFP associations with cancers

A

Hepatocellular carcinoma
Hepatoblastoma
Yolk sac tumor
Mixed germ cell tumor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

AFP associations with fetal anomalies

A

^AFP in neural tube defects
^AFP in abdominal wall defects
Decreased in down syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

b-HCG

A 
Hydatidiform moles
Choriocarcinomas
Testicular cancer
Mixed germ cell tumor
HCG=Hydatidiform, choriocarcinomas, germ cell (don't forget the balls!)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Where is b-HCG produced?

A

Syncytiotrophoblasts of the placenta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

CA15-3/CA27-29

A

Breast cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

CA 19-9

A

Pancreatic adenocarcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

CA 125

A

Ovarian cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Calcitonin

A

Medullary thyroid carcinoma (Parafollicular cells)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

CEA

A

CarcinoEmbryonicAntigen: very nonspecific
70% of colorectal and pancreatic cancers
Also seen in gastric, breast, medullary thyroid carcinomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Chromogranin

A

Neuroendocrine tumors and carcinoid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

PSA

A

Prostate specific antigen.
Prostate cancer
BPH
Prostatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Oncogenic EBV

A

Burkitt, hodgkin, nasopharyngeal, Primary CNS lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Oncogenic HBV/HCV

A

Hepatocellular carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Oncogenic HHV-8

A

Kaposi sarcoma

17
Q

Oncogenic HPV

A

Cervical and penile/anal carcinoma (types 16 and 18)

Head and neck cancer

18
Q

Oncogenic H. pylori

A

Gastric adenocarcinoma and MALT lymphoma

19
Q

Oncogenic HTLV-1

A

Adult T cell leukemia/lymphoma

20
Q

Oncogenic liver fluke (Clonorchis sinensis)

A

Cholangiocarcinoma

21
Q

Oncogenic Schistosoma haematobium

A

Squamous cell bladder cancer

22
Q

Psammomma bodies are found in which pathologies?

A 
PSaMMoma
Papillary thyroid carcinoma
Serous papillary cystadenocarcinoma of the ovary
Meningioma
Malignant mesothelioma
23
Q

Common primary tumors that metastasize to the brain

A

Lung>breast>prostate>melanoma>GI

24
Q

Common primary tumors that metastasize to the liver

A

Colon»stomach>pancreas

25
Q

Common primary tumors that metastasize to the bone

A

Prostate, breast>lung, thyroid, kidney

Pathology (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions