Tumor markers Flashcards
1
Q
AFP
A
Hepatocellular carcinoma Hepatoblastoma Yolk sac (endodermal sinus) tumor Testicular cancer Mixed germ cell tumor (co-secreted with beta-hCG)
2
Q
CA-19-9
A
Pancreatic adenocarcinoma
3
Q
CA-125
A
Ovarian cancer
4
Q
Calcitonin
A
Medullary thyroid carcinoma
5
Q
Calretinin (Vit D-depending Ca-binding protein)
A
Mesothelioma
6
Q
CEA
A
Colon cancer (good for assessing treatment response) Pancreatic cancer
7
Q
CD34, CD117
A
GIST
8
Q
Chromogranin
A
Neuroendocrine tumor
9
Q
Desmin
A
Smooth muscle and skeletal muscle sarcomas
10
Q
Glial fibrillary acidic protein (GFAP)
A
Glioma (astrocytoma, ependymoma)
11
Q
hCG
A
Gestational trophoblastic disease (hydatidiform moles and choriocarcinomas)
Testicular cancer
12
Q
Inhibin
A
Sex cord-gonadal stromal tumor
13
Q
PSA
A
Prostate cancer
14
Q
Thyroglobulin
A
Post-operative marker of thyroid cancer (but not medullary thyroid cancer)
15
Q
Alkaline phosphatase
A
Metastases to bone or liver
Paget disease of bone
Seminoma (placental ALP)
