Carcinogens Flashcards
1
Q
Aflatoxins (from Aspergillus, in stored rice and grains; induce p53 mutations)
A
Hepatocellular carcinoma
2
Q
Alkylating agents
A
Leukemia/lymphoma (side effect of chemo)
3
Q
Alcohol
A
SCC of oropharynx and upper esophagus
Hepatocellular carcinoma
4
Q
Arsenic (present in cigarette smoke)
A
SCC of skin
Lung cancer
Angiosarcoma of liver
5
Q
Asbestos
A
Lung carcinoma (higher incidence) Mesothelioma (lower incidence)
6
Q
Cigarette smoke
A
Transitional cell carcinoma of bladder SCC of esophagus RCC of kidney SCC of larynx Squamous cells and SCC of lung Pancreatic adenocarcinoma
7
Q
Nitrosamines (smoked foods)
A
Stomach carcinoma
8
Q
Aromatic amines (e.g. benzidine, naphthylamine - present in cigarette smoke)
A
Transitional cell carcinoma of the bladder
9
Q
Vinyl chloride (used to make PVC pipes)
A
Angiosarcoma of liver
10
Q
Nickel, chromium, berrylium, silica
A
Lung carcinoma
11
Q
Carbon tetrachloride
A
Centrilobular necrosis and fatty change of liver
12
Q
Radon
A
Lung cancer (2nd leading cause after cigarette smoke)
