Tumor Immunology Flashcards
It is a branch of medicine devoted to the study and treatment of tumors.
Oncology
It is commonly used to describe a proliferation of cells that produces a mass rather than a reaction or inflammatory condition.
Tumor
What are the Cellular adaptation?
•Atrophy
•Hypertrophy
•Hyperplasia
•Metaplasia
(AH2M)
It is the study of the antigen associated with tumors, the immune response to tumors, the tumor’s effect on the host’s immune status, and the use of the immune system to help eradicate the tumor.
Tumor Immunology
Tumor immunology is best to understood with a background on differences between _____ & ______.
Tumor cells;Normal cells
It act as central regulators of the growth in normal cells that code for proteins involved in growth and repair processes in the body.
Proto-oncogenes
It can cause uninhibited cell division if their expression is altered or if they are mutated.
Protooncogenes
The mutations or malfunctions of it remove growth-inhibitory signals can cause tumor.
Tumor suppressor genes
It is normally couteract proto-oncogenes by encoding proteins that prevent cellular differentiation.
Tumor suppressor genes
It is composed of cells that possess many of the attributes of the normal cells from which they arose but have accelerated or dysregulated growth.
Tumors
These are tumors that do not invade surrounding tissue and normal body function is largely preserved
Benign Tumors
It can invade surrounding tissues and greatly disrupt normal body function.
Malignant Tumors
It is when the malignant cells travel through the body, causing new foci of malignancy until body function is so disrupted that death occurs.
Metastasis
This type or tumor is usually encapsulated, Grow slowly, Nonspreading, minimal mitotic activity, and ressemble the parent tissue.
Benign Tumors
This type of tumor Increased in number of cels that accumulate, invasion of tissues, Dissemination by lymphatic spread within a body cavity,Metastasis, Nuclear cellular features, Receptors for integrin molecules.
Malignant Tumors