Hypersensitivity

Question 1

These are environmental antigens that typically elicits allergic responses in susceptible individuals

Answer 1

Allergens

Question 2

What are the AEROALLERGENS?

Answer 2

Pollens
Mold Spores
Animal Dander
Fecal material excreted by mites
Cockroaches

Question 3

Clinically adverse reflecting acquired immune response that are marked PHENOTYPICALLY.

Answer 3

Allergy

Question 4

It is an acute, generalized allergic reaction with simultaneous involvement of several organ systems, usually CARDIOVASCULAR, RESPIRATORY, CUTANEOUS, AND GASTROINTESTINAL.

Answer 4

Anaphylaxis

Question 5

Ana:_____;Phylaxis:_____

Answer 5

Ana: Opposite
Phylaxis: Protection

Question 6

refers to Anaphylaxis in which HYPOTENSION, with or without loss of consciousness.

Answer 6

Anaphylactic shock

Question 7

It is a condition in which the symptoms and signs of anaphylaxis occur in the ABSENCE OF AN ALLERGEN-ANTIBODY MECHANISM.

Answer 7

Anaphylactoid Reaction

Question 8

another term for allergy

Answer 8

Atopy

Question 9

In Atopy, a word meaning “strange disease” derived from the Greek for “_______”.

Answer 9

out of place

Question 10

____ of activated mast cells, basophils, and eosinophils release preformed primary mediators.

Answer 10

Degranulation

Question 11

In Degranulation, What are the preformed primary mediators?

Answer 11

Heparin
Histamine
Protease
Eosinophil chemotactic factor
Neutrophil chemotactic factor

Question 12

is a process of temporarily supressing immediate HYPERSENSITIVITY reactions by repeated injections of increasing amounts of the offending allergens

Answer 12

Desensitization

Question 13

can be defined as a NORMAL but EXAGGERATED/UNCONTROLLED immune response go an antigen that can produce inflammation,. cell destruction, or tissue injury.

Answer 13

Hypersensitivity

Question 14

It is the basis of ACUTE ALLERGIC REACTIONS caused by molecules released by mast cells when an allergen interacts with membrane-bound IgE.

Answer 14

Immediate Hypersensitivity

Question 15

It is often used synonymously with the term cell-mediated immunity

Answer 15

Delayed Hypersensitivity

Question 16

a PRIMARY immune response to an antigen and has no clinical consequences

Answer 16

Sensitization stage

Question 17

A SECONDARY immune response that id deleterious to the individual.

Answer 17

Effector Stage

Question 18

Distinguish Humoral hypersensitivities from cellular hypersensitivities

Answer 18

Older classification

Question 19

Characteristic :(Response time following challenge dose of antigen)

“Gradually rises to peak at 24-72hrs”

Answer 19

Delayed Hypersensitivity

Question 20

Characteristic :(Responsible cellular and chemical agents)
“ B cell product”

Answer 20

Immediate Hypersensitivity

Question 21

Characteristic :(Response time following challenge dose of antigen)

“Visible within minutes; diminished within few hours”

Answer 21

Immediate Hypersensitivity

Question 22

Characteristic :(Responsible cellular and chemical agents)

“T cell product”

Answer 22

Delayed Hypersensitivity

Question 23

Characteristic: (Passive transfer via)

“SERUM”

Answer 23

Immediate hypersensitivity

Question 24

Characteristic: (Passive transfer via)

“T Lymphocytes”

Answer 24

Delayed Hypersensitivity

Question 25

Characteristic: (Chemotherapy) “Steroids”

Answer 25

Delayed Hypersensitivity

Question 26

Characteristic: (Chemotherapy) “Antihistamine and Adrenergenic compounds”

Answer 26

Immediate Hypersensitivity

Question 27

Characteristic :(Target tissues) “Primarily smooth muscles; organs; vascular tissue”

Answer 27

Immediate Hypersensitivity

Question 28

Characteristic:(Target tissue) “No special targets; generalized response”

Answer 28

Delayed Hypersensitivity

Question 29

Characteristic:(Histology of skin response) “Erythema, Edema, and Wheal Formation; granulocytes predominate in early response; mononuclear cells increase in later response”

Answer 29

Immediate Hypersensitivity

Question 30

Characteristic:(Histology of skin response) “Erythema and Induration; little edema; no wheal; mononuclear cells predominate”

Answer 30

Delayed Hypersensitivity

Question 31

Characteristic:(Tissue Death) “Common”

Answer 31

Immediate Hypersensitivity

Question 32

Characteristic:(Tissue Death) “Uncommon”

Answer 32

Delayed Hypersensitivity

Question 33

Characteristic:(Relative ease of desensitization) “Easy: via formation of blocking antibodies”

Answer 33

Immediate Hypersensitivity

Question 34

Characteristic:(Relative ease of desensitization) “Difficult: mechanism unknown”

Answer 34

Delayed Hypersensitivity

Question 35

Newer system which consists of four categories emphasizing the kind of immunopathological damage incurred.

Answer 35

Gell and Coombs Classification

Question 36

In Gell and Coombs Classification, What type are mainly immunoglobulin-mediated?

Answer 36

Type I,II,III

Question 37

In Gell and Coombs Classification, What Type is mediated by T cells and is synonymous with delayed hypersensitivity.

Answer 37

Type IV

Question 38

In Gell and Coombs Classification, What type is also called Immediate Hypersensitivity?

Answer 38

Type I

Question 39

In Gell and Coombs Classification, What type reaction ade initiated by the binding of antibody to a cell membrane or to the extracellular matrix.

Answer 39

Type II

Question 40

In Gell and Coombs Classification,What type hypersensitivity reaction involve the interaction of antibodies with soluble molecules to make soluble antigen-antibody complexes.

Answer 40

Type III

Question 41

In Gell and Coombs Classification, What type of hypersensitivity reaction are those in which cells of the immune system directly attack host cell in the absence of antibody.

Answer 41

Type IV

Question 42

What atopic reaction that is called anaphylaxis and affects the entire body?

Answer 42

systemic atopic response

Question 43

What Atopic reaction is the allergic symptoms depend on the anatomic location?

Answer 43

Local atopic reaction