Tuesday October 22 Quest Preparation Flashcards

1
Q

what is facilitated diffusion

A

diffusion down a concentration gradient aided by proteins

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2
Q

what types of proteins for facilitated diffusion

A

both channel and carrier

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3
Q

which ion is most present inside the cell

A

potassium

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4
Q

what bases the selectivity of ion channels

A

binding sites based on hydrophobic/philic properties and size

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5
Q

what are the types of channels

A

voltage gated
ligand gated
mechanically gated

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6
Q

what are ligands

A

molecules that are used as keys to open a gated channel

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7
Q

whats an example of facilitated diffusion via carrier proteins

A

GLUT transporters that transport glucose to red blood cells down a gradient

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8
Q

whats an example of facilitated diffusion via channel proteins

A

aquaporins which allow water to travel faster than simple diffusion with a channel protein down a gradient

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9
Q

what is active transport

A

transportation of particles from low to high concentration (against gradient)

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10
Q

what form of transport requires ATP

A

active transport

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11
Q

at what step does the hydrolysis of ATP occur

A

the attachment of sodium ions

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12
Q

whats an example of active transport

A

glucose to epithelial cells in small intestine OR red blood cells maintaining sodium + potassium levels

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13
Q

what are the 3 uses of active transport

A

maintain sodium potassium levels
remove waste
take up essential nutrients

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14
Q

what is direct active transport

A

the transport of molecules/particles against its gradient (one particle)

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15
Q

what is an exergonic reaction

A

breakdown of ATP

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16
Q

what makes an exergonic reaction

A

direct active transport

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17
Q

what is indirect active transport

A

the transport of one particle with its gradient and another against its gradient

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18
Q

whats an example of indirect active transport

A

cotransport of glucose and sodium to an epithelial cell in the small intestine

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19
Q

what is endocytosis

A

bulk transport mechanism that moves particles into a cell through engulfing a vesicle

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20
Q

what is phagocytosis

A

ingestion of large solid particles

21
Q

whats an example of phagocytosis

A

when WBC’s project their membrane around foreign particles, engulf them, and becomes a phagosome
then fuses with a lysosome to break down matter and release nutrients

22
Q

what is pinocytosis

A

ingestion of bulk liquid particles

23
Q

what is exocytosis

A

the bulk transport of materials out of the cell or to the membrane

23
Q

what is an example of pinocytosis

A

the intake of extracellular liquid for a cell

24
what is an example of exocytosis
glycolipids produced in the er and modified in the golgi can be sent out to the membrane for repair
24
can undigested food be excreted out of the cell
yes
25
why are vesicles and membranes the same level of fluidity
their membranes are made of the same level of saturation or unsaturation
26
do gated ion channels span a membrane
yes
27
what way in terms of gradient do gated ion channels travel
down a gradient
28
what is resting membrane potential
the potential difference of the cell and extracellular environment
29
what is the typical resting membrane potential / potential difference in a neuron
-70mV
30
what is action potential
a stimulus that can cause an electrical impulse
31
what is an electrical impulse
temporary reversal in potential difference that can send signals
32
are voltage-gated channels open or closed during resting state
closed
33
describe the process of the gated ion channels in neurons
stimulus causes the sodium ion channel to open and the sodium diffuses from extracellular to cellular environment (depolarization) then the potassium channel opens and the diffusion of potassium from cellular to extracellular environment occurs (repolarisation)
34
channels can be called pores (T/F)
true
35
what shape is the inactivation gate for ion channels
spherical
36
what are ligand gated channels
ion channels that open when a molecule binds to it (ligand)
37
nicotinic acetylcholine receptors are ligand gated channels (T/F)
true
38
nicotinic acetylcholine receptors are in skeletal neuromuscular junctions (T/F)
true
39
can nicotine open nAchR
yes
40
what is the name of the sodium potassium pump as an enzyme
ATPase / ATPases
41
describe the working of the sodium potassium pump
pump is open to the inside and 3 sodium attaches the hydrolysis of ATP occurs conformational change and discards sodium to extracellular 2 potassium attaches conformational change and discards potassium in cell
42
what is indirect active transport
the transport of one molecule with its gradient and another against its gradient
43
what is a cotransporter protein
a protein that can transport 2 particles at once
44
what type of protein are cotransporter proteins
channel proteins
45
whats an example of indirect active transport
sodium dragging glucose along for the transport into epithelial cell in small intestine
46
what is an endergonic process
non-spontaneous absorption of energy