B2.1 Flashcards

Membranes and Membrane Transport

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1
Q

what macromolecules are in membranes

A

proteins
lipids
small carbs

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2
Q

what are the major classes of lipids

A

phospholipids
glycolipids
sterols

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3
Q

describe what a phospholipid looks like

A

modified glycerol molecule with a neg charged phosphate group and two fatty acid chains

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4
Q

describe phospholipids in an aqueous environment

A

tails point inward

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5
Q

where is cholesterol located

A

between tails

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6
Q

term for water loving and hating

A

amphipathic

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7
Q

what can pass through the membrane

A

steroids
lipid soluble
small uncharged (h20, o2)

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8
Q

what is permability reliant on

A

hydrophobic/hydrophilic nature

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9
Q

what is simple diffusion + example

A

the passive transport of molecules from high to low concentration
diffusion of oxygen from high to low concentration in red blood cells

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10
Q

what is a transmembrane protein

A

a protein that extends fully across a membrane (integral)

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11
Q

explain the polarity of integral proteins

A

top/outer part is hydrophilic and interacts with the heads, while the inner part is hydrophobic and interacts with the tails

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12
Q

explain the polarity of peripheral proteins

A

hydrophilic and interacts with the heads

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13
Q

4 functions of membrane proteins

A

cell - cell recognition
transport
receptors
enzymes

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14
Q

function of transport proteins + 2 types

A

facilitate movement
channel proteins
- form channels for movement
carrier proteins
- conformational change

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15
Q

function of recognition proteins

A

distinguish between self and non self cells with cell - cell recognition

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16
Q

function of receptor proteins

A

binding of molecules to this protein can facilitate reactions or processes

17
Q

function of enzyme proteins

A

catalyze reactions

18
Q

what are aquaporins

A

integral proteins that speed up the movement of water down a concentration gradient

19
Q

Facilitated diffusion

A

movement of solutes down a concentration gradient monitored by size and polarity
movement is mediated by size and polarity
aided by channel and carrier proteins

20
Q

what type of protein is used for ion pumps

A

channel proteins

21
Q

what decides the ion used for the channel protein

A

binding sites being highly specific

22
Q

what forms of stimuli can open/close

A

changes in voltage
binding of molecules (ligand gated)

23
Q

how do carrier proteins transfer molecules

A

undergo conformational change and binds to the solute

24
Q

what is active transport used for

A

transporting nutrients against a concentration gradient
remove waste
maintain concentrations

25
Q

two types of active transport

A

direct –> regular, uses atp
indirect –> movement of one down its gradient makes another against its gradient

26
Q

two classes of recognition proteins

A

gated ion channels
specific carrier proteins (GLUT)

27
Q

types of glycolipids

A

glycoglycerolipids –> based on glycerol molecules
glycophingolipids –> derivatives of sphingosine

28
Q

how do glycolipids contribute to membrane stability

A

forms h bonds with mobile water

29
Q

functions of glycolipids and glycoproteins

A

cell - cell recognition
cell adhesion
cell signalling

30
Q

what is glycocalyx

A

sticky layer formed by surface of glycolipids and glycoproteins

31
Q

what contributes to the fluid mosaic model

A

lipids and proteins can move freely in the membrane

32
Q
A