Tuesday - Male Reproductive Path - Twomey Flashcards

1
Q

Acute bacterial Prostatitis

A

gram -, same as UTI

sx - fever chills dysuria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Chronic bacterial prosatitis

A

same organisms but non-specific sx
low back pain, dysuria, pelvic pain
may have UTI’s
Dx - prostate massage –> culture fluid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Most common form of protatitis

A

chronic abacrterial

- probz just culture (-) bugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

labs with prostatitis

A

increase PSA
- 30% acually decrease

abx and nsaid may be ineffective

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Who gets BPH

A

old dudes. 70% of 60y/o

50% become symptomatic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Cause of BPH

A

androgens - DHtestosterone increases with age

estrogen - estradiol levels increase with age –> induce more androgen receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Sx of BPH

A

you have to pee at night more
hard to pee when you start
small stream
dribbling

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Complications of BPH

A

Obstruction - urgent
incomplete emptying
Infection
Infarction

renal failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Tx for PBH

A
5 alpha reductase inhibitor
 - reduces DHT - 50% reduction of PSA
alpha 1 blocker
 - relax smooth muscle
TURP, cryotherapy, laser, ultrasound
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

most common side of vericocele

A

left side, becaase in goes into the left renal vein (smaller calliber = higher resistance)
- right –> goes to IVC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Testicular descent phases, contraolled by:

A

phase 1 - transabdominal - controlled by mullarian inhibiting substance

phase 2 - inguinosacral - controlled by androgens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

How many people have Cryptorchid

A

25% if prmature
4-6% patent - closes in 3 months
1-2% after first year

it’s usually unilateral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

if cryptorchid is uncorrected:

A

sterile if bilateral
infertile if unilateral
can lead to hernia
oncogenic!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Treatment of cryptorchid

A

orchiopexy

do it before 2 years to be fertile, 10 years to prevent cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Infertility with oligospermia

A
less than 20 mill sperm /mL
testicular
post testicular - obstruction
 - normal biopsy
 - may have no vas deferens if Cycstic fibrosis
40% idioparthic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Epididamo-Orchitis

A
bacterial
 - same bugs as UTI
 - sti's
granulomatous
 - TB, fungi (crypto)
viral
 - mumps!
17
Q

Tortion is usually art or vein?

what happens if you don’t repair it in time

A

Vein
- before 30 yo
need surgical repair within 4 hours - or hemorrhagic infarct

18
Q

Vericocele how common?

A

25% of adults
more common of left
can cause infertility

19
Q

Testicular neoplasms two classes

A
germ cell tumors - most common in denmark
 - seminoma (he puts this in a seprate category, but it's here in FA)
 - yolk sac
 - choriocarcinoma
 - teratoma
 - embryonal carcinoma
sex cord stromal tumors
 - sertoli, leydig, lymphoma
20
Q

precursor to neoplasia in germ cells

other factors that increase risk

A

Intratubular germ cell neoplasia
low % in blacks
high % in kleinfelters

21
Q

Seminoma

A
50% of germ cell tumors
most common in 30's
homogenius (fish flesh) look. 
waterly cytoplasm
can have syncytiatrophoblasts (normally in placenta) - secrete hCG
cross crossing fibrosis
22
Q

Embryonal Carcinoma

A

2nd most common - usually in 20’s, bad prognosis
have dark hemorrhages, looks worse that seminoma.

looks pretty pleomorphic

23
Q

yolk sac tumor

A

usually in infants. under 3 yo
homogeneuus, but yellow looking. looks like glomerulus
Schiller-Duval bodies

24
Q

Choriocarcinoma

A

always has beta-hCG
real bad
small
metastisizes to lungs and brain

25
Q

teratoma

A

malignant in males, not females
benign in kids increased hCG and/or AFP in 50%

lots of cysts - endo,meso,ecto derm

26
Q

mixed tumors

A

60% of the germ cell tumors actually have characteristics of several types

27
Q

metastasis of germ cell tumors

A

lymphatic spread
- ipsilateral usually
hematogenous spread
- lung, brain

histo can be different than primary tumor

28
Q

Staging

A

I, II, III
70% are stage I - 98% 2 year survival

Stage 2 - 90% 2 year survival

29
Q

2 Markers

what are they indicative of

A

AFP - usually marker of fetus, made from yolk sac tumor and seminomas (and hepatocellular carcinoma)

HCG - choriocarcinoma

30
Q

Treatment for germ cell tumors

A

orchectomy if stage I

orchectomy and radiation if stage II

31
Q

Non-germ cell tumors

A

sertoli - gynecomastia

leydig - produce androgens –> gynecomastia, precocious puberty. golden brown color

Testicular lymphoma
- older men, usually not primary. real bad

32
Q

Hernia/hyrodcele

types:

A

failure to obliderate the inguinal canal

inguinal hernia - communication with the perinineal cavity

hydrocele - transilluminating

spermatocele - cyst from efferent ducts - filled w/ sperm