Monday - Male Reproductive Histo - Aubie Aubie Flashcards
Testis function: 2
Exocrine - spermatozoa
Endocrine - testosterone, inhibin
Excretory Ducts function: 2
transport - spermatozoa
storage - secretory products
Accessory glands functions
fluid production
Penis funtions
pee + sex
Scrotum functions
thermoregulation
Testis
capsule called?
emryonic sac called?
divisions of tubules called?
Tunica albuginea - capsule
Tunica vaginalis - parietal and visceral layers
Lobules - CT between tubulaes made from albuginea
Type of epithelium in the seminiferous tubules
4-8 layers of stratified complex
- supporting cells (sertoli cells)
- gem cells
identifying a sertoli cell
oval
distinct nucleus.
how to identify a spermatogonia
attached to the basement membrane
primary spermatocytes
large speckled nuclei
spermatids look like
round nucleus
spermatozoa look like
enlongated
flagella
Types of spermatogonia - functions
Dark type A - reserve. divide to make pale type a
(dark people are reserved)
Pale Type A - renewing stem cells. make more of themselves. differentiate to type b
Type B - make mature gametes
primary spermatocytes. look and function:
large - diploid
enter meiosis I
secondary spermatocytes. look and function:
haploid - short existence
enter meiosis 2
Cells don’t completely divide - form what
syncytia
- spermatids
Spermatids
round nuclei
after both meiotic divisions
syncytium
where are the mitochondria in a spermatozoa
o==————-~
^ there
matuation of spermatids is called:
4 phases
spermiogenesis
- golgi - form acrosome from golgi
- cap - acrosome granules fuse
- acrosomal - head orients, nuclear elongation
- maturation - residual body is shed - phagocytosed by sertoli - released into semineferous tubule
Blood testis barrier formed by what?
from what junction proteins?
Sertoli cells
Zonula occudens
Sertoli cells
what receptor?
They make what binding protein?
make what hormone?
other function?
FSH receptor
Androgen binding protein
make inhibin
nutrition/nourishment
In between lobules, what stuffis there. One important one
interstitial space
- collagenous fibers
- blood and lymph vessels
- fibroblasts, macrophages, mast
- mesenchyme
- cells of LEYDIG~
What do the cells of leydig do?
what do they look like?
Make testosterone
they’re pretty big, light staining, eosionophilic. lots of ER
in groups
crystalloid inclusions
Where does LH bind? what does that do?
To the LH receptor on Leydig cells
secretes testosterone –> negative feed back to hypothal