Tuburculosis Flashcards

1
Q

cause of tuburculosis

A

mycobacterium tuberculosis

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2
Q

how is TB spread?

A

person to person, droplet nuclei, cough, sneeze, air must have pulmonary or laryngeal tuburculosis

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3
Q

which stains were used for the photo of droplets

A

Ziehl-Neelsen or Kinyoun which are carbol fushin methods

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4
Q

what is the shape of mycobacterium tuburculosis
also motility, grow speed and acid or base fast

A

rod-shaped, non-motile, slow-growing, acid-fast

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5
Q

where is a common place for US travelers to get TB?`

A

Mexico

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6
Q

bovine TB is caused by what

A

consuming unpasturized dairy products from infected cattle

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7
Q

can you get TB by eating or drinking after someone?

A

no

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8
Q

can you get TB from dishes, utensils, clothing, or linenes

A

no

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9
Q

do you need to wear caps, gowns, or gloves with TB?

A

no

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10
Q

is airplane transmission higher?

A

no

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11
Q

infectious TB on airplane, should they travel?

A

no

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12
Q

which TB is infectious

A

TB of the lung

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13
Q

how is contagious status determined?

A

chest radiograph, sputum tests, symptoms and treatment

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14
Q

what organization has issued guidelines for passengers who might have been exposed to TB on an airplane

A

WHO

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15
Q

how is the tubercle bacilli inhaled

A

nose or mouth

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16
Q

carried down the ___ into the lung by droplet nucleus

A

trachea

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17
Q

once they reach the aveoli they multiply freely for how long?

A

2-10 weeks

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18
Q

where can the bacili spread unopposed

A

lymph nodes in center of the chest

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19
Q

how do bacili spread to other parts of the body

A

from lymphatic system to bloodstream

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20
Q

suseptible areas to spreading?

A

upper portions of lung, kidneys, spine, brain, or bone

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21
Q

when did latent TB become a reportable

A

2016

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22
Q

latent TB characteristics

A

bacili in body, positive skin test, normal chest x ray, no sx, no sputum, infected but not infectious

23
Q

without treatment, ____ of infected people with TB will develop TB at some point

A

5-10 %

24
Q

half of the people who develop actual TB will do so within

A

first two years of infection

25
Q

active TB characteristics

A

bacili in body, positive skin test, abnormal chest x-ray, sputum, sx, infected and infectious

26
Q

TB is the ____ leading killer after COVID

A

2nd

27
Q

how many people got TB in 2022

A

10.6 million

28
Q

which country has highest TB

A

India then Indonesia, china, phillipines, pakistan, nigeria, bangladesh, and south africa

29
Q

in 2019 how many countries accounted for 87% of TB

A

30

30
Q

how many counties account for 2/3 of Tb cases

A

8

31
Q

what percent of infections involve the lungs

A

70-80%

32
Q

symptoms of TB

A

prolonged cough, fever, hemoptysis, weight loss, anorexia, night sweats

33
Q

infected organs

A

lymph nodes, pleura, bones and joints, brain, kidney, bladder, genitalia

34
Q

condition is also referred to as

A

consumption

35
Q

risk of TB is much higher in who

A

immunosuppressed, 8-10% in HIV patients, people receiving TNF factor inhibitors for rheumatoid arthritis

36
Q

latent TB drug therapies

A
  • isoniazid for 9 months
  • isoniazid and rifapentine weekly for 12 weeks WITH observation
  • rifampin for 4 months
37
Q

TB drug therapies

A

directly observed for 6-9 months
isoniazid, rifampin, ethambutol, pyrazinamide x 2 months
then isoniazid and rifampin for 4-7 months

38
Q

multi drug resistant TB treatment

A

4-6 drugs for 18-24 months

39
Q

drug sensitive TB cost

A

49 k

40
Q

multi drug resistant tb cost

A

393 k

41
Q

XDR tb cost

A

758 k

42
Q

rifampin ADRs

A

hepatotox, lupus, peripheral neuropathy, monoamine toxicity

43
Q

rifampin monitoring parameters

A

flushing of hands and feet

44
Q

isoniazid ADRS

A

GI upset, flu like syndrome, organge discoloration of body fluids, thrombocytopenia

45
Q

isoniazid monitoring

A

LFTs, CBC, SCr, LFTs

46
Q

pyrazinamide ADRs

A

hyperuricemia, arthralgia, rash

47
Q

pyrazinamide monitoring

A

uric acid

48
Q

ethambutol ADRs

A

optic neuritis (blind spot, color blindness), hyperuricemia

49
Q

ethambutol monitoring

A

baseline and monthly visual color vision

50
Q

prevention of TB etiquite

A

adequate ventilation, cough etiquette, avoidance of crowds, protective gear, screening, vaccination

51
Q

WHO reccomends which vaccine at birth in most developing countries

A

Calmette-Guerin (BCG)

52
Q

is BCG reccomended in US

A

no, interferes with LTBI testing

53
Q

which test is preferred in pre and post travel testing for people vaccinated with BCG

A

IRGA preferred cause TST is interferred with

54
Q
A