Tuburculosis Flashcards

1
Q

cause of tuburculosis

A

mycobacterium tuberculosis

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2
Q

how is TB spread?

A

person to person, droplet nuclei, cough, sneeze, air must have pulmonary or laryngeal tuburculosis

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3
Q

which stains were used for the photo of droplets

A

Ziehl-Neelsen or Kinyoun which are carbol fushin methods

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4
Q

what is the shape of mycobacterium tuburculosis
also motility, grow speed and acid or base fast

A

rod-shaped, non-motile, slow-growing, acid-fast

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5
Q

where is a common place for US travelers to get TB?`

A

Mexico

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6
Q

bovine TB is caused by what

A

consuming unpasturized dairy products from infected cattle

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7
Q

can you get TB by eating or drinking after someone?

A

no

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8
Q

can you get TB from dishes, utensils, clothing, or linenes

A

no

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9
Q

do you need to wear caps, gowns, or gloves with TB?

A

no

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10
Q

is airplane transmission higher?

A

no

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11
Q

infectious TB on airplane, should they travel?

A

no

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12
Q

which TB is infectious

A

TB of the lung

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13
Q

how is contagious status determined?

A

chest radiograph, sputum tests, symptoms and treatment

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14
Q

what organization has issued guidelines for passengers who might have been exposed to TB on an airplane

A

WHO

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15
Q

how is the tubercle bacilli inhaled

A

nose or mouth

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16
Q

carried down the ___ into the lung by droplet nucleus

A

trachea

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17
Q

once they reach the aveoli they multiply freely for how long?

A

2-10 weeks

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18
Q

where can the bacili spread unopposed

A

lymph nodes in center of the chest

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19
Q

how do bacili spread to other parts of the body

A

from lymphatic system to bloodstream

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20
Q

suseptible areas to spreading?

A

upper portions of lung, kidneys, spine, brain, or bone

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21
Q

when did latent TB become a reportable

A

2016

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22
Q

latent TB characteristics

A

bacili in body, positive skin test, normal chest x ray, no sx, no sputum, infected but not infectious

23
Q

without treatment, ____ of infected people with TB will develop TB at some point

24
Q

half of the people who develop actual TB will do so within

A

first two years of infection

25
active TB characteristics
bacili in body, positive skin test, abnormal chest x-ray, sputum, sx, infected and infectious
26
TB is the ____ leading killer after COVID
2nd
27
how many people got TB in 2022
10.6 million
28
which country has highest TB
India then Indonesia, china, phillipines, pakistan, nigeria, bangladesh, and south africa
29
in 2019 how many countries accounted for 87% of TB
30
30
how many counties account for 2/3 of Tb cases
8
31
what percent of infections involve the lungs
70-80%
32
symptoms of TB
prolonged cough, fever, hemoptysis, weight loss, anorexia, night sweats
33
infected organs
lymph nodes, pleura, bones and joints, brain, kidney, bladder, genitalia
34
condition is also referred to as
consumption
35
risk of TB is much higher in who
immunosuppressed, 8-10% in HIV patients, people receiving TNF factor inhibitors for rheumatoid arthritis
36
latent TB drug therapies
- isoniazid for 9 months - isoniazid and rifapentine weekly for 12 weeks WITH observation - rifampin for 4 months
37
TB drug therapies
directly observed for 6-9 months isoniazid, rifampin, ethambutol, pyrazinamide x 2 months then isoniazid and rifampin for 4-7 months
38
multi drug resistant TB treatment
4-6 drugs for 18-24 months
39
drug sensitive TB cost
49 k
40
multi drug resistant tb cost
393 k
41
XDR tb cost
758 k
42
rifampin ADRs
hepatotox, lupus, peripheral neuropathy, monoamine toxicity
43
rifampin monitoring parameters
flushing of hands and feet
44
isoniazid ADRS
GI upset, flu like syndrome, organge discoloration of body fluids, thrombocytopenia
45
isoniazid monitoring
LFTs, CBC, SCr, LFTs
46
pyrazinamide ADRs
hyperuricemia, arthralgia, rash
47
pyrazinamide monitoring
uric acid
48
ethambutol ADRs
optic neuritis (blind spot, color blindness), hyperuricemia
49
ethambutol monitoring
baseline and monthly visual color vision
50
prevention of TB etiquite
adequate ventilation, cough etiquette, avoidance of crowds, protective gear, screening, vaccination
51
WHO reccomends which vaccine at birth in most developing countries
Calmette-Guerin (BCG)
52
is BCG reccomended in US
no, interferes with LTBI testing
53
which test is preferred in pre and post travel testing for people vaccinated with BCG
IRGA preferred cause TST is interferred with
54