Tuberculosis Flashcards

1
Q

What is the mm of induration which indicates a positive test?

A
>5mm is positive for:
HIV PTs
Recent contact w/ TB PT
Fibrotic changes on CXR
Immunosuppresed PTs (I.e. on prednisone)
PTs with organ transplants
>10mm positive for
Recent immigrants <5yrs
IVDA
Children <4 y.o.
Residents/employees in high risk settings
Mycobacteriologic personnel

> 15mm positive for
Person without known risk factors

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2
Q

What are some possible reasons for false negatives on Skin tests?

A

HIV
Steroid use
Anergy
Malnutrition

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3
Q

What is the most specific and sensitive TB test?

A

Quantiferon gold

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4
Q

Which drug can cause peripheral neuropathy?

A

Isoniazid (INH)

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5
Q

If someone receives the BCG vaccine; it can cause positive results on which tests?

A
Skin test (PPD) Mantoux Test
BUT NOT THE QUANTIFERON GOLD
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6
Q

If someone receives the BCG vaccine; it can cause positive results on which tests?

A
Skin test (PPD) Mantoux Test
BUT NOT QUANTIFERON GOLD
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7
Q

What are the four first line drugs for Tb?

A

Isoniazid (INH)
Rifampin (RIF)
Ethambutol
Pyrazinamide

Drugs taken for 6 to 9 months

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