Tuberculose Flashcards

1
Q

voie de distribution possible

A

hématogène, bronchogène, lymphatique

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2
Q

FDR de multi-résistance

A

ATCD tuberculose ttt non complètement
Chine, Inde, Ex union-soviétique
contacts antérieur de TB multirésistantes

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3
Q

Signes faisant rechercher tuberculose urinaire ?

A

leucoturie

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4
Q

ATB pouvant faire élever ALAT :

A

rifampicine, pyrinizamide, isionazide

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5
Q

localisation des anomalies radio :

A

lobes supérieur et postérieur

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6
Q

type pleurésie TB

A

exsudat lymphocytaire clair

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7
Q

séquelle TB

A

nodules calcifié, dilatation bronches, aspergillome, lésions fibreuses rétractiles

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8
Q

seuil détection BAAR en examen direct

A

> 10^3 bacilles / ml

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9
Q

CI pyrazinamide

A

Ih, IR

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10
Q

déclaration obligatoire à qui ?

A

CLAT, ARS

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11
Q

temps ttt TB neuro-méningé

A

9-12 mois

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12
Q

durée isolement respiratoire

A

15j ttt plein

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13
Q

indication du despitage ITL

A

VIH+, ITL récente <2ans, <15 ans migrant, avant instauration TTT immunosuppresseur

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14
Q

anergie tuberculinique :

A

faux positif
VIH rougeole sarcoidose

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15
Q

suspicion ITL IDR

A

D >10mm sans vaccination au BCG préalable
D augmente 10 mm sur 2 IDR en 3 mois = virage tuberculinique

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16
Q

indication chimioprophylaxie primaire ITL

A

enfant <2ans
enfant ID
ttt avant résultat pendant 8-12sem jusqu’à 2eme dosage

17
Q

combien CD4 haut risque de passage ITL –> TM chez patient VIH + ?

A

<200 CD4/mm3

18
Q

4 examen ++ important à faire en cas de TB miliaire :

A

fibroscopie bronchique
ECBU
hemoc
myeloculture (que si leuconeutropénie)

19
Q

TTT chimie-prophylaxie :

A

6 mois isoniazide (que adulte)
3/4 mois rifampicine + isoniazide

20
Q

supplémentation grossesse isoniazide et rifampicine si ttt au 3e trimestre

A

vit B6
vit K1