Trypanozoma cruzi Flashcards

1
Q

Host

A

armadillo, opossum, agouti, rodents, dogs, cats, humans

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2
Q

Carrier

A

Rejuviid - kissing bug (triatomid)

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3
Q

Morphology

A

C shaped, kinoplast, central nucleus

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4
Q

Lifecycle

A

trypomastigote in blood, amastigote in muscle or nerve fiber

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5
Q

symptoms

A

acute (tryp)- fever, edema, lymphodenopathy, degeneration tissue, anemia, hepatosplenomegaly, EKG abnorm, CNS involvement, death

chronic (amast)- fever, constipation, abdom distention, EKG abnorm, cardiomegaly, apical aneurysm, megacolon/esophagus (destruction of myenteric plexus)

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6
Q

Treatment

A

Nifurtimox, benznidazole, only in trypomastigote phase

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7
Q

control

A

insecticide treated nets

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8
Q

diagnosis

A

xenodiagnosis, thin smear, ELISA, PCR

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