Trypanosoma b. rhodesiense and gambiense Flashcards
1
Q
Geography
A
gambienese - west africa, rhodesiense - east africa
2
Q
vector
A
tse tse fly
3
Q
host
A
pigs, wild animals
4
Q
lifecycle
A
trypomastigotes in blood, lymph, csf
5
Q
symptoms
A
enlarged cervical lymoh nodes (winterbottom sign), intermittent fever, progressive weakness, anemic, wasted, comatose (r - acute, g - chronic)
6
Q
treatment
A
early - IV suramin or eflornithine - removes everywhere except CNS
melarsoprol - crosses BBB
7
Q
control
A
aerial, ground, cattle spraying of insecticides, biconical trap
8
Q
diagnosis
A
blood film, trypomastigotes in aspirated gland juice, CSF, PCR, ELISA
