Trypanosomiasis And Leishmaniasis Flashcards
What is the causative agent of Changas disease?
Trypanosoma cruzi
What is the causative agent of dourine?
Trypanosome equiperdum
What is the causative agent of Nagana?
Trypanosome brucei, T. Congolense, T. Vivax
What is the causative agent of Surra?
Trypanosoma evansi
What is the causative agent of canine leishmaniasis?
Leishmania infantum
What are the transmission routes for typanosomes?
Insect-vectored trypanosomes
Latrogenic transmission via blood-contaminated needles, syringes, etc.
Transplacental transmission
What does euryxenous mean?
Can infect a wide range of animals
Are Trypanosoma host-specific or euryxenous?
both, differs by species
What transmits Nagana disease?
Tsetse flys (glossina spp.)
When will you most likely find lots of trypansomomes in the blood in Nagana disease?
Acute phase
What does acute disease of Naga disease look like?
high parasitemia with extensive hemorrhages of mucosa and serosal surfaces of the body
What does chronic disease look like for Nagana disease?
cattle become anemic and emaciated with signs of severe wasting
What animals are affected by Tsetse-transmitted trypanosomes?
domestic ruminants, equids, pigs, dogs and cats
What is the vector of Surra disease?
Tabanid flies (horseflies) and vampire bats
What is a key symptom of chronic Surra disease?
Hindleg paralysis
What is a non-tsetse Diptera-vectored trypanosome?
Surra disease
Where is Surra disease transmitted?
north africa, asia, and tropical america
What is a sexually transmitted trypanosome?
Dourine disease - Trypanosome equiperdium
What trypanosome is transmitted without a vector?
Trypansomsoma equiperdum - Dourine disease
How is dourine disease transmitted?
Sexual contact
What is silver dollar plaques a key symptom of?
Dourine Disease - Trypanosome equiperdum
What are the acute stapes of Dourine disease?
swelling on genitali, mucoid discharge in which T. equiperdum can be demonstrated, silver dollar plaques
What are the chronic stages of dourine disease?
emaciation, paresis, intermittent fever, and finally death
Where is dourine endemic?
asia, africa, middle east, eastern eurpoe, south and central america