Clinical Case Example Cryptosporidiosis Flashcards

1
Q

what are the two significant species of Cryptosporidium in humans?

A

C. parvum (zoonotic)
C. hominis

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2
Q

what is a cryptosporidium species that is in cattle and is zoonotic?

A

C. parvum

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3
Q

what kills children under the age of 5 every day more than AIDS and malaria?

A

diarrhea

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4
Q

what is the most common cause of waterborne diarrhea outbreaks in people?

A

Cryptosporidium

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5
Q

how does cryptosporidium affect immunocompromised vs immunocompetent people?

A

immunocompromised makes it more chronic and debilitating

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6
Q

what is the second leading cause of diarrhea in heifer calves?

A

Cryptosporidium

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7
Q

what does Cryptosporidium require to undergo exocystation?

A

stomach acids
digestive enzymes
bile acids

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8
Q

what is the goal of the infective oocysts?

A

to survive and shed more out into the environement

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9
Q

what does Cryptosporidium do to villus absorptive epithelial cells?

A

loss of villus absorptive epithelial cells -> malabsorption and maldigestion -> diarrhea

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10
Q

what is happening here? what is causing this?

A

villus atrophy/blunting
Cryptosporidium

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11
Q

what are the common clinical signs of Cryptosporidium?

A

watery diarrhea, dehydration, abdominal pain, weight loss, nausea and vomiting, fever, death

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12
Q

what are the treatment options for Cryptosporidium?

A

no effective drug treatment
no vaccines
supportive care

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13
Q

what is the only FDA approved drug for Cryptosporidium?

A

nitazoxanide

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14
Q

what are the modes of transmission for Cryptosporidium?

A

fecal oral
infected food, water, soil

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15
Q

what is the host of C. parvum, C. andersoni, C. bovis, C. ryanae?

A

cattle (calves)

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