Cryptosporidiosis and Coccidian Diseases Flashcards
Is cryptosporidium considered a coccidia?
NO
what is a zoite?
elongated, motile cell
what is an oocyst?
environmentally resistant stage
what does oocysts contain?
infective sporozoites, located within sporocysts
Are most cryptosporidium host specific or broad?
mostly host specific
what does cryptosporidium damage?
infect/damage mucosal epithelial cell
what type of life cycle does Cryptosporidium have?
direct
what type of transmission does Cryptosporidium that infect the GI tract have?
feecal-oral
what type of transmission does Cryptosporidium that infect the respiratory tract have?
droplet transmision
what is Schizogeny
meronts divide -> merozoites -> infect host cells -> merontsm -> repeat
what is gametogeny?
subset of merozoites infect host cells and develop into gamonts -> gametes
what is fertilization?
zygotes -> ooxysts
what is the sporogeny of Cryptosporidium?
oocysts sporulate (sporozoites develop) endogenously (inside host)
what is a thin-walled oocyst?
sporozoites excyst and reinfect host
what is a thick-walled oocyst?
infective when shed, viable for months, resists disinfectants
what does gastrointestinal cryptosporidiosis cause?
gastroentereitis
what is seen in most hosts infected with gastrointestinal cryptosporidiosis?
mild to moderate, watery, self-limited diarrhea
what are the hosts of C. parvum?
ruminants, horses
what are the hosts of C. baileyi?
poultry
what is a large risk of C. parvum?
zoonotic, transmit to humans
what are the primary hosts of respiratory cryptosporidiosis?
avian hosts
what cryptosporidium causes respiratory and gastrointestinal cryptosporidiosis
C. baileyi
how do you diagnose Cryptosporidiosis?
clinical signs and…
microscopic ID of oocysts
ELISA
PCR
what is used to treat cryptosporidiosis?
nirazoxanide (calves)
paraomomycin (dogs and cats)
supportive therapy (main use)
how can cryptosporidiosis be prevented?
enforce strict sanitation and good management
isolate affected animals
what does Eimeria spp. largely impact?
ruminants and poultry
what do most Eimeria spp. infect?
GI tract - enterocytes and/or cells in lamina propria
Are the predilection sites of Eimeria always the same?
no varies by species
what type of life cycle does Eimeria have?
direct
How is Eimeria transmitted?
fecal-oral
what is the enteric cycle of Eimeria spp.?
schizogeny, gametogeny, fertilization, oocyst production
what is the sporogony of EImeria spp.?
oocysts typically sporulate exogenously (outside host)
what is the host of E. tenella?
chicken
what is the host of E. bovis?
bovine
how do you diagnose Eimeria induced coccidiosis?
clinical signs and…
microscopic ID - fecal float
what is the treatment of Eimeria-induced coccidiosis?
self-limiting - spontaneous recovery w/out treatment is common
anticoccidial drugs
supportive thearpy
what anticoccidial drug should be used to treat Eimeria-induced Coccidiosis in cattle?
amprolium
what anticoccidial drug should be used to treat Eimeria-induced Coccidiosis in small ruminants?
amprolium
what anticoccidial drug should be used to treat Eimeria-induced Coccidiosis in poultry?
amprolium
what is the preventention/control of Eimeria-induced Coddidiosis?
what type of life cycle does Cystoisospora spp.?
direct life cycle with fecal oral transmission + transmission via paratenic host
what is the transmission of Cystoisospora spp.?
fecal-oral
Are Cystoisospora spp. host specific?
strictly host specific
what does Cystoisospora spp. infect?
GI tract - primary enterocytes, host cell ruptured/destroyed
what is the Cytoisospora that infects swine?
C. suis
what is the Cytoisospora that infects dogs?
C. canis
what is the Cytoisospora that infects felines?
C. felis & C. rivolta
what are the definitive hosts of Toxoplasma gondii?
felids (wild and domestic)
How are felids typically infected with Toxoplasma gondii?
eating tissue cysts harbored by infected intermediate hosts
what is the enteric cycle of Toxoplasma gondii?
schizogeny and gametogeny in felid enterocytes -> oocysts shed in feces
How do oocysts sporulate for Toxoplasma gondii?
oocysts sporulate exogenously
what is the consequence of Toxoplasma gondii oocysts sporulating exogenously?
infective to intermediate hosts and felids