Trigger 8 - Alzheimer’s disease and amyloid targeting therapies Flashcards
Define Dementia
Dementia is the loss of cognitive functioning (e.g., thinking, remembering, and reasoning) to such an extent that it interferes with daily life and activities.
True or False: Dementia is a normal part of aging.
False. Dementia is not a normal part of aging.
Fill in the Gap: Dementia prevalence increases with advancing _________.
Age.
What is the most common form of dementia?
a) Vascular dementia
b) Frontotemporal dementia
c) Alzheimer’s disease
d) Lewy body dementia
c) Alzheimer’s disease
Describe Early Onset Alzheimer’s Disease (EOAD):
EOAD occurs in individuals under 65 years of age and often has a significant genetic component.
Describe Late Onset Alzheimer’s Disease (LOAD):
LOAD occurs in individuals over 65 years of age and is generally sporadic in nature.
True or False: Alzheimer’s disease is characterized by short-term memory loss as its first symptom.
True
Fill in the Gap: Alzheimer’s disease develops to more severe memory problems, confusion, disorientation, personality changes, and problems with ________ and _________.
Language and speech.
Which of the following is NOT a sign or symptom of Alzheimer’s disease?
a) Misplacing items
b) Difficulty in decision making
c) Heightened ability to understand visual images
d) Social withdrawal
c) Heightened ability to understand visual images
Define Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common form of dementia, characterized by progressive memory loss and cognitive decline, leading to interference with daily functioning and activities.
True or False: Alzheimer’s disease is more prevalent in men than in women.
False. More women have Alzheimer’s disease than men.
Fill in the Gap: Globally, over ______ million people have some form of dementia.
55 million.
Which of the following is a common early symptom of Alzheimer’s disease?
a) Difficulty in problem solving
b) Reduced ability to understand visual images
c) Mood swings
d) Misplacing items
d) Misplacing items
Describe Dementia Prevalence in the UK
In the UK, over 1 million people are currently affected by dementia, which accounts for approximately 1 in 11 individuals over the age of 65.
True or False: Dementia prevalence is expected to decrease by 2050.
False. Dementia prevalence is expected to increase, with cases in the UK projected to reach at least 1.6 million by 2050.
Fill in the Gap: Age is the biggest risk factor for _________.
Dementia
Which form of Alzheimer’s disease has a larger genetic component?
a) Early onset
b) Late onset
c) Both have equal genetic components
d) Neither has a genetic component
a) Early onset
Define Neuropathology
Neuropathology refers to the study of diseases of the nervous system, including the structural and biochemical changes that occur in the brain and nervous tissue.
True or False: Alzheimer’s disease primarily affects the peripheral nervous system.
False. Alzheimer’s disease primarily affects the central nervous system, particularly the brain.
Fill in the Gap: One of the signs of Alzheimer’s disease is confusion with ______ and ______.
Time and place.
True or False: Memory loss is a common sign of Alzheimer’s disease.
True
Fill in the Gap: Alzheimer’s patients may have difficulty in ________ items.
Misplacing
Which of the following is a symptom of Alzheimer’s disease?
a) Enhanced ability in problem solving
b) Increased ability to complete complex tasks
c) Mood swings
d) Improved understanding of visual images
c) Mood swings
Define: Repetitive Speech and Writing Issues
Repetitive speech and writing issues refer to the tendency of individuals with Alzheimer’s disease to repeat the same words, phrases, or sentences and to have difficulties with written communication.