Tremor Flashcards
A tremor is bilateral and associated with purposeful movement and includes head tremor and voice tremor is likely…
Essential tremor
A tremor that decreases with alcohol is likely..
Essential
What is the mainstay of tremor treatment?
Beta blockers, primidone
What part of the brain is most implicated in essential tremor?
Thalamus
What pattern of inheritance does ET follow?
AD
What is the most common pathologic sign of Parkinson’s disease?
Loss of pigment in substantia nigra
Intracytoplasmic Lewy bodies
What are some common Parkinson’s mimics?
Multiple system atrophy - very similar, tremor less prominent and symmetric
Corticobasal ganglionic degeneration - also asymmetric
Progressive supra nuclear palsy - down gaze palsy, frequent falls, no tremor
What are the testament options for Parkinson’s?
Levodopa, dopamine agonists, MAO inhibitors (selegine, rasagilene) j
What therapy has been shown to reduce levodopa induced dyskinesia?
Amantidine
What medications are most responsible for drug induced Parkinsonism?
Metoclopramide, antipsychotic