Trematodes Flashcards
What are the 2 groups of Trematodes (Flukes)?
1) Tissue Flukes - infects lungs and bile ducts
- Paragonimus westermani = lung fluke
- Clonorchis sinensis and Fasciola hepatica = liver flukes
2) Blood Flukes - inhabit the blood
- Schistosoma
What is Schistosoma’s life cycle?
-Life Cycle: -Diagnostic stage = eggs released from
urine/stool
-Infective stage = snails release cercariae into
human’s skin
What are the symptoms of Schistosomiasis?
-Symptoms: Skin = dermatitis
GI =abdominal pain, bloody diarrhea
Urogenital = cystitis and urethritis
Diagnosis of Schistosomiasis? Treatment? Prevention?
- Diagnosis: eggs in urine/stool; Porcelain bladder
- Treatment: Praziquantel
- Prevention: Avoid swimming around snails
What is Fasciolopsis buski’s (Giant intestinal fluke) life cycle?
-Life Cycle: -Diagnostic stage = immature eggs released
from intestine/stool
-Infective stage = snails release metacercariae
onto aquatic plants which humans consume
What are the symptoms of Fasciolopsis buski? Diagnosis? Prevention? Treatment?
-Symptoms: epigastic pain, nausea, diarrhea, edema, ascitis
-Diagnosis: history of consuming uncooked water chestnuts; eggs in stool
Prevention: avoid consuming uncooked water chestnuts
Treatment: Praziquantel
What is Fasciola hepatica’s life cycle?
-Life Cycle: -Diagnostic stage = Fasciola eggs released
from intestines/stool
-Infective stage = snails release metacercariae
onto aquatic plants which humans consume
What are the symptoms of Fasciola hepatica? Diagnosis? Prevention? Treatment?
- Symptoms: fever and chills, eosinophilia, hepatitis, hyperplasia and blockage of bile duct
- Diagnosis: history of consuming uncooked watercress, eggs in stool
- Prevention: avoid consuming uncooked watercress
- Treatment: RESISTANT to Praziquantel; use Triclabendazole
What is Opisthorchis (Clonorchis) sinensis’ (Chinese liver fluke) life cycle?
-Life cycle: Diagnostic stage = eggs released from bile
duct/stool
Infective Stage = Ingestion of undercooked
freshwater fish
What are the symptoms of Opisthorchis sinensis? Diagnosis? Prevention? Treatment?
- Symptoms: liver necrosis, tenderness, and dysfunction, hepatomegaly, and jaundice
- Diagnosis:history of consuming undercooked fish, eggs in stool
- Prevention: avoid consuming undercooked fish
- Treatment: Praziquantel
What is Paragonimus westermani’s life cycle?
-Life Cycle: Diagnostic stage = eggs released from sputum or stool Infective stage = consumption of undercooked freshwater crab (shellfish)
What are the symptoms of Paragonimus westermani? Diagnosis? Prevention? Treatment?
- Symptoms: dry cough, pleurisy, rusty-brown sputum, epilepsy if migrates to brain
- Diagnosis: history of consuming undercooked crab, eggs in sputum/stool
- Prevention: avoid undercooked crab
- Treatment: Praziquantel
What food group is related to Paragonimus westermani?
Crab/shellfish
What food group is related to Fasciolopsis buski?
Water chestnuts
What food group is related to Fasciola hepatica?
Watercress
What food group is related to Opsithorchis (Clonorchis) sinensis?
Freshwater fish