Trematodes Flashcards
Intestinal species
- Fasciolopsis buski
- Heterophyes heterophyes
- Metagonimus yokogawai
Liver species
- Fasciola hepatica
- Clonorchis sinensis
Lung specie
Paragonimus westermani
Dioecious flukes
• Schistosoma mansoni
• Schistosoma japonicum
• Schistosoma haematobium
Heterophid flukes
Heterophyes heterophyes
Metagonimus yokogawai
____ contain a lidlike structure that under the appropriate conditions flips open to release its contents for further development, called an _____
-eggs
-operculum
Larval stages
Miracidium
Sporocysts
Rediae
Cercariae
Metacercariae
is ciliated, and its prominent internal features include eyespots, various penetration glands, and numerous excretorycells and tubules
Miracidium
are simple, tubular or branched germinal sacs
Sporocysts
are tubular germinal sacs which possess an oral sucker and rudimentary digestive system, a birth pore, and small ambulatory appendages. This one contains developing cercariae.
Rediae
resemble miniature adults, with a similar body shape, digestive system and ornamentation to the adults they will become
Cercariae
Large intestinal fluke
Fasciolopsis buski
Fasciolopsis buski
MORPHOLOGY: EGGS
• Are broadly ellipsoidal, operculated
• Measures 130 to 150 µm long by 60 to 90 µm • Difficult to distinguish from Fasciola hepatica eggs.
Fasciolopsis buski
Morphology: Adult
• Somewhat oblong and fleshy
• Averagesize is 5 by 1.5cm.
• Have a poorly-developed oral and ventral suckers.
• Reside in the intestine of mammalian host
Fasciolopsis buski
- intermediate host:
- genera:
- reservoir host:
- snails
- hippeutis and segmentina
- rabbits, pigs, and dogs
Sheep liver fluke
Fasciola hepatica
Fasciola hepatica main definitive hosts
domestic and wild ruminants
Fasciola hepatica
* definitive host:
* intermediate host (and its genera):
* accidental host:
- DEFINITIVE HOSTS: sheep, cattle, and goats, camelids, cevids, and buffalo
- INTERMEDIATE HOSTS: Snails in the genera Lymnaea, Galba, Fossaria and Pseudosuccinea.
- ACCIDENTALHOST:Humans
Fasciola hepatica disease
FASCIOLOPSIS “SHEEP LIVER ROT”
is limited to the areas of the Far East, including parts of China, Thailand, Taiwan, and Vietnam, as well as regions in India and Indonesia
Fasciolopsis buski
is found worldwide, particularly in areas in which sheep andcattleare raised
Fasciola hepatica
Fasciolopsis buski and Fasciola hepatica treatment
- Infections with Fasciolopsis buski can be treated with PRAZIQUANTEL
- Infections with Fasciola hepatica has been successfully treated with DICHLOROPHENOL(Bithionol).TRICLABENDAZOLE is more effective.
• It is equipped with a distinct operculum opposite to a small knob.
• A thick rim is strategically located around the operculum and is referred to as shoulders.
C. sinensis eggs
“CHINESE or ORIENTAL LIVER FLUKE”
C. sinensis
Important foodborne pathogen and cause of liver disease in Asia
C. sinensis
C sinensis lab diagnosis and treatment
- recovery of eggs from stool specimens or duodenal aspirates. (Enterotest may also be perform)
- Praziquantel or Albendazole
C. sinensis reservoir hosts
fish-eating mammals, dogs, and cats
A minute intestinal fluke
H. heterophyes
The smallest human fluke
Metagonimus yokogawai
Shell thickness
M. yokogawai:
H. heterophyes:
- thin
- thick
• An opercular rim (shoulders) surrounds the prominent operculum.
• An obvious terminal shell thickening is located in the end opposite the operculum.
P. westermani eggs
• The cuticle of P. westermani possesses spines
• It has a lobed ovary located anterior to two branching testes.
• Possess oral and ventral suckers
P. westermani adult worm
Oriental lung fluke
P. westermani
P westermani
First IH:
Second IH:
- snail
- crustaceans
Paragonimiasis disease phases
- Acute Phase (invasion and migration)
- Chronic Phase:
• PARAGONIMASIS: PULMONARY DISTOMIASIS - CEREBRAL PARAGONIMIASIS
Manson’s blood fluke
S. mansoni
Blood fluke
S. japonicum
Bladder fluke
S. haematobium
Has a prominent large lateral spine
S. mansoni eggs
Has a small lateral spine
S. japonicum eggs
Has a large, prominent, terminal spine
S. haematobium eggs
Theo nlyTrematodes that have separate sexes, with the female residing in a gynecophoral canal within the male.
Schistosoma species
M. yokogawai first IH: snail in the genus ____
Semisulcospira
H. heterophyes first IH/main IH in Southeast Asia
Cerithideopsilla cingulate
Heterophid flukes second IH
fresh/brackish water fish
Heterophid flukes treatment
Praziquantel
• Schistosoma mansoni IH are
• Schistosoma japonicum IH are
• Schistosoma haematobium IH are
Biomphalaria spp.
Oncomelania spp.
Bullinus spp.
Upon release from the snail, the infective cercariae swim, penetrate the skin of the human host and shed their forked tails,becoming _________
Schistosomulae
is more frequently found in the superior mesenteric veins draining the small intestine
• S.japonicum
occurs more often in the inferior mesenteric veins draining the large intestine
• S.mansoni
most often inhabits in the vesicular and pelvic plexus of the bladder, but can also be found in the rectal venules.
• S. haematobium
considered the second most serious parasitic infection, only after malaria, in terms of mortality and morbidity
Schistosomiasis
Schistosoma spp reservoir hosts
monkeys, cattle and other livestock, rodents
is believed to originate in the Old World because it is primarily in parts of Africa
S. mansoni
is limited in the Far East which includes parts of China, Indonesia, and the Philippines
S. japonicum