Trematodes Flashcards

1
Q

Trematodes Adult Worms

A
  • Usually flat
  • Elongated
  • Leaf shaped
  • Two cup-shaped muscular suckers
  • Oral sucker
  • Ventral sucker used for attachment
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2
Q

Hermaphroditic Fluke

A
  • Bisexual
  • Highly branched reproductive organs
  • Paragonimus westermani
  • Fasciola hepatica
  • Clonorchis sinensis
  • Fasciolopsis buski
  • Heterphyes heterophyes
  • Metagonimus yokagawai
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3
Q

Unisexual Adult Worms

A
  • Both male and female
  • Schistosoma mansoni
  • Schistosoma japonicum
  • Schistosoma haemtobium
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4
Q

Trematodes Life Cycle

A

1) Adult lives in specific organs or blood
2) Eggs are found in particular specimen depending on species
3) Eggs contaminate environment
4) Eggs contain larvae (mirachidium)
5) Mirachidium infects specific snail species
6) Mirachidium forms sporocyst, which then develops into cercariae
7) Cercariae are free swimming

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5
Q

Sites Eggs are found

A

1) Sputum - lung fluke (P. westermani)
2) Feces - intestines (S. mansoni, S. japonicum, F. buski, H. heterophyes, F. hepatica, C. sinensis)
3) Urine - bladder (S. haematobium)

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6
Q

Cercariae pathways

A

1) Schistosomes (species found in blood)
- Cercariae emerge from snail and penetrate skin of humans
2) In F. buski and F. hepatica
- Encyst attaches to water plants and eaten by humans
3) H. heterophyes, C. sinensus, & P. westermani
- Enters the second intermediate host (fish or crabs) which is eaten by humans

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7
Q

Trematodes Pathology

A

Lesions which depend upon location, number of adult worms, and effect eggs and metabolic products have on host

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8
Q

Paragonimus westermani Distribution

A

Found in far east
Japan, China, Micronesia, New Guinea, Korea, Vietnam, Thailand, Cambodia, India, and Philippines

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9
Q

Paragonimus westermani Symptoms

A

Chest pain
Cough
Blood tinged sputum (appears pepper-like and blood streaked)

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10
Q

Paragonimus westermani Adult

A

Encyst in the lung
Frequently in pairs
1 mm x 5 mm

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11
Q

Paragonimus westermani Egg

A

85 x 55 mm
Terminal shell thickening
Shouldered operculum
Operculum has rim

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12
Q

Fasciola hepatica Distribution

A

Sheep and cattle-raising countries

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13
Q

Fasciola hepatica Symptoms

A

Causes liver cirrhosis

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14
Q

Fasiola hepatica Adult

A

35 mm x 15 mm

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15
Q

Fasiola hepatica Egg

A

150 x 90 um
Operculated

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16
Q

Clonorchis sinesis Distribution

A

Found in far east
Japan, Korea, Vietnam, and China

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17
Q

Cloronochis sinesis Symptoms

A

Inflammatory changes
Feeding of adult in biliary passages
Jaundice due to bile duct pathology
Diarrhea
Abdominal pain

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18
Q

Clonorchis sinesis Adult

A

Measures 19 mm x 3.5 mm

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19
Q

Clonorchis sinesis Egg

A

30 um x 16 um
Small terminal knob
Thickened rim around operculum - “shouldered operculum”

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20
Q

Clonorchis sinesis Diagnostic Stage

A

Egg in stool

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21
Q

Fasciolopsis buski Distribution

A

China, India, Vietnam, and Thailand

22
Q

Fasciolopsis buski Adult

A

20-30 mm x 10 mm

23
Q

Fasciolopsis buski Pathology

A
  • Mucosal ulcers
  • Pain
  • Nausea
  • Diarrhea
24
Q

Fasciolopsis buski Egg

A

Same as F. hepatica
Cannot differentiate between the two

25
Fasciolopsis buski Infectious Stage
Ingestion of water chestnuts contaminated with metacercaria
26
Fasciolopsis buski Diagnostic Stage
Egg in stool
27
Schistosoma japonicum Distribution
Far East
28
Schistosoma japonicum Common Name
Oriental Blood Fluke
29
Schistosoma japonicum Pathology
- Granuloma of liver or intestines - Cirrhosis - Most pathogenic
30
Schistosoma japonicum Egg
80 x 60 um Small indistinguishable lateral spine
31
Schistosoma japonicum Diagnostic Stage
Egg in stool
32
Schistosoma mansoni Distribution
Africa, Middle East, and South America
33
Schistosoma mansoni Pathology
Bilharzia Granuloma of liver, intestines, and bladder May cause cirrhosis
34
Schistosoma mansoni Egg
160 um x 80 um Prominent lateral spine
35
Schistosoma mansoni Diagnostic Stage
Egg in stool
36
Schistosoma haematobium Distribution
Nile River Valley, African, Middle East
37
Schistosoma haematobium Pathology
Squamous cell carcinoma of bladder
38
Schistosoma haematobium Egg
160 um x 80 um Terminal spine
39
Schistosoma haematobium Diagnostic Stage
Eggs in urine
40
Schistosoma dermatitis Distribution
Cosmopolitan
41
Schistosoma dermatitis Pathology
Dermatitis (inflammation and localized edema)
42
Schistosoma dermatitis Infectious Stage
Cercariae penetration of skin
43
Schistosoma dermatitis Diagnostic Stage
Rash after swimming
44
Schistosoma dermatitis Common Name
Swimmer's Itch Clam Digger's Itch Whirl Pool Dermatitis
45
Paragonimus westermani Common Name
Oriental Lung Fluke
46
Paragonimus westermani Infectious Stage
Ingesting raw crayfish with metacercariae
47
Paragonimus westermani Diagnostic Stage
Eggs in sputum
48
Fasciola hepatica Common Name
Sheep Liver Fluke
49
Fasciola hepatica Infectious Stage
Ingesting watercress contaminated with metacercariae
50
Fasciola hepatica Diagnostic Stage
Egg in stool Travel history
51
Clonorchis sinesis Common Name
Chinese Liver Fluke
52
Clonorchis sinesis Infectious Stage
Ingesting under cooked fresh water fish contaminated with metacercariae