Treatments Flashcards
GORD
PPI + H2 antagonists + Lifestyles changes
Peptic Ulcers
H-pylori = CLATM ( 2 out of Clarithromycin, Amoxicillin, Tetracycline, Metronidazole + PPI)
No infections = Antacids, Antacids, PPI
Crohn’s
Stop smoking
Corticosteroids
Immunosuppressants - Azathioprine, Mercaptopurine or Methotrexate
Surgical resection
UC
Mesalazine, analgesia, surgical resection
IBS
Lifestyle modification
Infective gastroenteritis
Rehydration
BRAT ( Bananas, Rice, Applesauce and toast)
Pancreatitis
Acute = Fasting, analgesia Chronic = Enzyme replacement
Gallstones
Medical - Ursodiol
Surgical - Cholecystectomy
Hepatitis
B - Vaccine available but treatment mostly symptomatice
Appendicitis
Appendectomy
Bowel Obstruction
Endoscopic stenting or bowel resection if perforation or peritonitis
Hernias
Some left as asymptomatic
Surgical repair
ACS
Acute = MONAC + PCI Chronic = Lifestyle changes, Aspirin/ Clopidogrel + ACEi, B-blockers and Ca-blockers, Statin
Angina
Modify risk factors
GTN spray, B/Ca-Blockers, Aspirin and Statin
AF
Rate control - B-blockers/Digoxin
Rhythm Control - Chemical (Amiodarone) or Electrical (Shock)
Thromboprophylaxis - Warfarin
Hypertension
1) < 55 = ACEi, >55 or Black = Ca-blockers
2) ACEi + Ca-blocker
3) Add Thiazide diuretic
4) Consider Sprinonolactone
DVT
Treatment dose of LMWH
LVF
Acute = Furosemide Chronic = ACEi + B-blockers
CHF
Lifestyle changes
ACEi + B-blockers + Duiretics
Breast Abscess
Advise to continue breastfeeding and give analgesia
Abx - flucloxacillin
If does not settle then FNA and culture
Fibrocystic Disease
Analgesia and well supported bra
Ductal Papilloma
Excision - Microdochetomy or total duct excision
Breast Carcinoma
Excision - Wide local or total mastectomy then Chem/Radiotherapy
Tamoxifen for 5 years post
T1 Diabetes
Insulin
T2 Diabetes
Depending on severity
Lifestyle advice
Metformin + Gliclazide
Hypothyroidism
Levothyroxine
Hyperthyroidism
Block and replace - Carbimazole + Levothyroxine
Radioactive Iodine
Thyroidectomy
Cushings
If pituitary or adrenal adenoma then surgical removal
Ketoconazole - inhibits cortisol
Iron Deficiency Anaemia
Ferrous Salts orally
Treat underlying cause if found
Macrocytic Anaemia
If B12 or Folate deficiency treat with supplements
B12 = Hydroxycobalmin
Folic acid tablets
If both must give B12 first
Osteoarthritis
Encourage exercise, weight loss, dietary changes
Analgesia, Corticosteroid injections and joint replacements
Gout
Acute = NSAIDs, Analgesia, Colchicine Chronic = Allopurinol prophylaxis
Septic Arthritis
Empirical Flucloxacillin/ Erythromycin + fusidic acid
Drain and clean joint
Replace prosthetic joint
Immobilise joint in early stages but mobile again to avoid contractures
Prolapsed disc
Bed rest and analgesia + physio
Surgery if cauda equina symptoms
Depression
Talking therapy, support groups, sort out underlying problems
SSRIs, Tricyclics
Anxiety
Talking therapies - Bio-psycho-social approach
CBT
SSRI’s, Tricylics, Benzo’s
Alcohol dependance
AA groups etc
Acute withdrawal = Pabrinex + Benzo’s
Delirium
Treat underlying cause
Halloperidol/ Lorazepam - sedatives
Dementia
Pt centred care
Donepezil
Stroke/TIA
Ischaemic:
Within 4.5 hrs = Alteplase (TPA), outside 4.5 = Aspirin
Chronic = Combination of Aspirin, Clopidogrel and Dipyridamole
Haemorrhagic = Reverse anticoagulants with prothrombin concentrates or surgical clipping or repair
SAH
Surgical prevention of further bleeding
Long term = lifestyle changes
Epilepsy
Sodium valproate, Carbemazepine, Levitarecetam, Lamotrigine, Phenytoin
Bacterial Meningitis
IV/IM Benzylpenicillin
Nutritional support and analgesia
Corticosteroids
Migraine
Analgesia + antiemetics
Severe = triptans
Prophylaxis - B-blockers, amitryptilline
Tension headache
Simple OTC analgesia
Massage
Relaxation techniques
Chronic = Amitriptyline
Parkinsons
Levodopa + Carbidopa/Benseazide
UTI
Uncomplicated - Nitrofurantoin/ Trimethoprim
Fluids and analgesia
Pyelonephritis
Rest, fluids and analgesia
Abx - Ciprofloxacin/Co-amoxiclav empirically
Hydronephrosis
Partial block and no infection = fluids, analgesia
Complete block = Catheter/stenting
Infection = Abx
AKI
Treat underlying cause if possible
Fluids, stop nephrotoxic drugs, treat complications - Hyperkalaemia, acidosis, pulmonary oedema
CKD
Lifestyle and diet changes
Review medications
BP + DM control
Dialysis / RRT if severe
BPH
Alpha blockers - Doxazosin
5-alpha-reductase inhibitors - Finasteride
Surgery if very large
Prostatic carcinoma
Prostatectomy + Chemo/radiotherapy
Acute asthma
High flow O2, Nebulised salbutamol, antimuscarinic, IV hydrocortisone or oral prednisolone
COPD
Stop smoking
Inhalers - Salbutamol, Salmeterol, Tiotropium, ICS, Oral prednisolone
Oxygen therapy
Bronchial Carcinoma
NSCLC - Neo-adjuvatn chemo to downstage then surgical resection and then adjuvant chemo/radiotherapy
SCLC - Combined chemo/radiotherapy - 5yr survival = 25 %
Pneumothorax
Tension = Large bore cannula decompression
Chest drain
O2 therapy
If recurrent then pleurodesis
Pleural effusion
Treat underlying disease
Tap effusion for symptomatic relief
Chest drain or pleurodesis
Lobar Pneumonia
CAP - Amoxicillin/macrolide - add fluclox if stap aureus suspected
HAP - Co-amox
Pulmonary Embolus
LMWH/Fondaparinux + 100% O2
Warfarin for 3 months post
Rivaroxaban prophylaxis
Peripheral vascular disease
Lifestyle modification
B-blockers, antiplatelets and peripheral vasodilators
Surgery - angioplasty/ bypass
AAA
< 5.5 cm = monitor
> 5.5 cm = Endovascular stenting or open resection
Varicose veins
Reassure few serious complications
Lifestyle advice - avoid standing/sitting for long periods of time
Can be removed for cosmetic reasons