Treatment post splenectomy Flashcards
1
Q
What conditions can result in hyposplenism?
A
Sickle cell Active chronic graft-vs-host disease Coeliac disease Splenectomy may be indicated in: Thrombocytopenia Severe haemolytic anaemia; spherocytosis Rupture Hypersplenism with splenomegaly
2
Q
What bacteria are those with a dysfunctional spleen most at risk from?
A
Encapsulated bacteria:
Streptococcus pneumoniae
Meningococcus
Haemophilus influenzae B
3
Q
What will the blood film show in asplenic patients?
A
Howell-Jolly Bodies Target Cells Lymphocytosis Neutrophilia Decreased production of IgG and IgM Reactive thrombocytosis
4
Q
When should immunization occur in a splenectomy?
A
If elective; at least 2 (ideally 4-6) weeks prior to surgery
Prophylactic antibiotics post surgery
Emergency: immunize at least 2 weeks post surgery and when well
Prophylactic antibiotics to be started immediately
5
Q
What vaccinations are indicated in those with hyposplenism?
A
Hib/MenC (haemophilus influenzae B and meningococcus C)
PPV (pneumococcal)
MenACWY (meningococcus ACWY)
6
Q
What antibiotics are recommended for prophylaxis in hyposplenism?
A
Amoxicillin
