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Oncology > Treatment > Flashcards

Treatment Flashcards

1
Q

What are alkylating agents?

A

Anti-proliferative drugs
Bing to akyl groups and cause apoptosis

Cyclophosphamide, busulfan

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2
Q

What are some examples of angiogenesis inhibitors?

A

Bevacizumab , aflibercept

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3
Q

What are antimetabolites?

A

Alter metabolism, DNA and protein synthesis

Methotrexate, 5-fluorouracil

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4
Q

What antioestrogens?

A

Aromatase inhibitors - letrozole, anastrozole

Oestrogen receptor antagonists - tamoxifen

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5
Q

What are antitumour antibiotics?

A

Inturrupt DNA function

dactinomycin, doxorubicin, mitomycin, bleomycin

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6
Q

What are topoisomerase inhibitors?

A

Interrupt regulation of DNA winding

Etoposide

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7
Q

What are vinca alkaloids and taxanes?

A

Spindle poisons - target cell division

Vincristine, vinblastine, docetaxel

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8
Q

What is given for palliation?

A

Pain - morphine
Agitation and anxiety - midazolam
N&V - haloperidol, levomepromazine
Secretions - hyoscine or glycopyrronium

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Oncology (7 decks)

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