Paraneoplastic syndromes Flashcards
What malignancies can cause hypercalcaemia by pseudohyperparathyroidism?
Lung - non-small cell squamous Oesophagus Skin Cervix Breast Kidney
What malignancies can cause SIADH?
Lung - small cell
Prostate
Lymphomas
Prostate
What malignancies can cause Cushing’s?
Lung - small cell
Pancreas
Thymus
Carcinoid
What malignancies can cause neuropathy?
Lung Breast Myeloma Hodgkins GI
What malignancies can cause Lambert Eaton syndrome?
Lung - Small cell (predominant cause)
GI
Breast
Thymus
What malignancies can cause dermato/polymyositis?
Lung
Breast
Ovary
GI
What malignancies can cause acanthosis nigricans (velvety, hyperpigmented skin)?
GI
What malignancies can cause pemphigus (blistering of skin and mucus membranes)?
Lymphoma
Thymus
Kaposi’s sarcoma
What malignancies can cause hypertrophic osteoarthropathy?
Lung - non small cell adenocarcinoma
What malignancies can cause high serotonin (preistalisis, bronchoconstriction)?
Lung - non small cell bronchial carcinoid
What malignancies can cause high beta-HCG (gynaecomastia/galactorrhoea)?
Lung - non small cell carcinoma
What malignancies cause encephalomyelitis?
Ovarian teratoma - anti NMDA
What malignancies cause hyperCa by ectopic VitD production?
H/NH Lymphomas
What malignancies cause polycythemia?
Renal
Liver
Cerebellar hemangioma
What malignancies cause cerebellar degeneration?
Gynae - anti-Yo Abs
Small cell lung - anti Hu Abs