Paraneoplastic syndromes Flashcards

1
Q

What malignancies can cause hypercalcaemia by pseudohyperparathyroidism?

A
Lung - non-small cell squamous 
Oesophagus
Skin
Cervix
Breast
Kidney
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2
Q

What malignancies can cause SIADH?

A

Lung - small cell
Prostate
Lymphomas
Prostate

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3
Q

What malignancies can cause Cushing’s?

A

Lung - small cell
Pancreas
Thymus
Carcinoid

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4
Q

What malignancies can cause neuropathy?

A
Lung
Breast
Myeloma
Hodgkins
GI
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5
Q

What malignancies can cause Lambert Eaton syndrome?

A

Lung - Small cell (predominant cause)
GI
Breast
Thymus

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6
Q

What malignancies can cause dermato/polymyositis?

A

Lung
Breast
Ovary
GI

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7
Q

What malignancies can cause acanthosis nigricans (velvety, hyperpigmented skin)?

A

GI

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8
Q

What malignancies can cause pemphigus (blistering of skin and mucus membranes)?

A

Lymphoma
Thymus
Kaposi’s sarcoma

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9
Q

What malignancies can cause hypertrophic osteoarthropathy?

A

Lung - non small cell adenocarcinoma

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10
Q

What malignancies can cause high serotonin (preistalisis, bronchoconstriction)?

A

Lung - non small cell bronchial carcinoid

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11
Q

What malignancies can cause high beta-HCG (gynaecomastia/galactorrhoea)?

A

Lung - non small cell carcinoma

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12
Q

What malignancies cause encephalomyelitis?

A

Ovarian teratoma - anti NMDA

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13
Q

What malignancies cause hyperCa by ectopic VitD production?

A

H/NH Lymphomas

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14
Q

What malignancies cause polycythemia?

A

Renal
Liver
Cerebellar hemangioma

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15
Q

What malignancies cause cerebellar degeneration?

A

Gynae - anti-Yo Abs

Small cell lung - anti Hu Abs

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