Treating Medical GI Dz Flashcards

1
Q

What are some diagnostics that can help you determine the severity of a case of colic?

A

(Ultrasound, abdominocentesis (look at the gross appearance, protein concentration, and lactate), and blood work (PCV, TP, blood lactate available on site (with the right equipment); +/- CBC, chem, blood gas)

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2
Q

What about the following things would indicate to you that you need to refer a colic case?

  • Pain
  • Heart rate
  • CRT
  • Reflux
  • Rectal
A
  • Pain (If it is unrelenting and/or only briefly controlled with sedation)
  • Heart rate (Persistently elevated HR, >60 bpm)
  • CRT (Slow)
  • Reflux (Large amount of net reflex (> 6 to 8 liters))
  • Rectal (Abnormal findings such as tight tenia bands, lots of distended bowel)
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3
Q

For the following scenario, assess the % dehydrated:

Skin tent of 2-3 seconds, mucous membrane moisture is fair, CRT is 1-2 seconds, PCV is 40-50%, and the TP is 6.5-7.5 g/dL

A

(4-6%)

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4
Q

For the following scenario, assess the % dehydrated:

Skin tent of 3-5 seconds, mucous membranes are sticky, CRT is 2-4 seconds, PCV is 50-65% and TP is 7.5-8.5 g/dL

A

(7-9%)

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5
Q

For the following scenario, assess the % dehydrated:

Skin tent is > 5 seconds, mucous membranes are dry, CRT is >4 seconds, PCV is >65% and TP is >8.5 g/dL

A

(>9%)

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6
Q

What is the comfortable oral fluid delivery volume for a 500 kg horse?

A

(10 L/30 min)

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7
Q

What is the issue with using plain water for repeated administration of fluids?

A

(It will lead to depletion of electrolytes stored in the cecum/colon)

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8
Q

Optimally you would make up for any fluid deficits quickly so how much of the deficit total do you want to administer in the first hour of fluid replacement?

A

(40-50%, give up to 10 L over first 30 minutes, then wait 30 minutes, then give up to another 10, repeat until 40-50% of deficit is administered, if the horse tolerates give the rest over 4-6 hours, add in losses and maintenance per hour)

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9
Q

What should you be monitoring throughout your oral fluid plan?

A

(Monitor for reflux, do not want to add more fluids if there is reflux, should also monitor protein/check for edema because they can become hypoproteinemic once rehydrated)

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10
Q

Oral fluids are effective in treating large colon impactions if what two things are true?

A

(There is GI motility and there is little net reflux)

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11
Q

What is the reflection coefficient?

A

(How readily a molecule can pass through a membrane, if it 0 = easy, if it is 1 = difficult, the RC is tissue specific (ex brain is near 1, liver is near 0))

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12
Q

Give some broad examples of diseases that decrease oncotic pressure due to low blood protein.

A

(Gut inflammation causing PLE, PLN, hepatopathy, peritoneal and/or pleural effusion, starvation, malabsorption)

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13
Q

Give some broad examples of diseases that decrease osmotic pressure due to electrolyte loss.

A

(Gut inflammation interfering with sodium absorption and retention, water overload, pleural and/or peritoneal effusion, ruptured bladder, and adrenal dysfunction)

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14
Q

Reduced membrane selectivity results when there is vasculitis, give some broad examples of diseases that induce vasculitis.

A

(Endotoxemia, infectious, and immune mediated)

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15
Q

What are some indications for a plasma transfusion?

A

(TP < 4 g/dL especially if the drop is rapid, edema, harsh/wet lung sounds + increased resp rate, and/or thickened bowel)

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16
Q

What is the formula used to determine how much plasma a horse needs to replace protein volume?

A

(Desired protein concentration minus measured protein concentration multiplied by 5% body weight all divided by donor protein concentration; or can just do 4 L per 1 g/dL desired for a 400-500 kg horse)

17
Q

What should you monitor every 5 minutes for the first 30 minutes of a plasma transfusion (given at 0.5 ml/kg)?

A

(Heart rate, respiratory rate, and temperature; if no signs of reaction (increased HR, RR, or temp, agitation, muscle fasciculations) gradually increase rate to 40 mls/kg/hr)

18
Q

What do you expect to occur to your TP when administering hetastarch for hypoproteinemia?

A

(It will go down bc hetastarch is not measurable on a refractometer)

19
Q

What is the main goal of treating vasculitis?

A

(Find and treat the cause, in the meantime can give NSAIDs and/or pentoxifylline)