Travel Related Infections Flashcards

1
Q

Rickettsia

A

Gram negative

Cocci and bacilli

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2
Q

Spirochaete

A

Spiral shaped

Cause syphilis

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3
Q

Acute infection

A

Less than 10 days

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4
Q

Sub acute infection

A

Presentation 10 - 21 days after exposure

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5
Q

Chronic

A

More than 21 days

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6
Q

Insect tick bite

A

Malaria
Dengue
Rickettsia

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7
Q

Contaminated food or water

A

Brucellosis

Salmonella

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8
Q

5 main species of plasmodium

A
Falciparum - Africa
Vivax - India 
Ovale - India 
Malariae 
Knowlessii
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9
Q

Incubation for malaria

A

Bitten 1 week ago

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10
Q

Presentation of malaria

A

Fever
Chills
Sweats

Cycle every 3rd/4th day

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11
Q

Mechanism of malaria

A
  1. Sporozites from the mosquito enter human blood
  2. Invade hepatocytes
  3. Form schizonts which multiply and mature into merozoites
  4. Lyase hepatocytes releasing merozoites systemically
  5. Invade and lyse RBCs
  6. Some merozoites become gametocytes which remain in the blood stream for several days and infect other mosquitos
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12
Q

Why is travel history important

A

Different strains of pathogen are:

  • antigenically different
  • impacts on protection and detection
  • antibiotic resistance
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13
Q

Risk factor for histoplasmosis

A

Caves

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14
Q

Myiasis

A

Fly larva from bot fly invades

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